Results 121 to 130 of about 70,967 (306)
Quantum Biology Operates the Human Brain
This paper proposes that human brain function is mediated by quantum biological mechanisms operating at the 12Hz alpha brainwave frequency. Four quantum principles govern human brain function: quantum tunneling, quantum entanglement, quantum superposition, and the quantum observer effect.
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Quantum dynamics for classical systems with applications of the number operator [PDF]
, 2013 Mathematics is increasingly applied to classical problems in finance, biology, economics, and elsewhere. Quantum Dynamics for Classical Systems describes how quantum tools—the number operator in particular—can be used to create dynamical systems in which
Bagarello, Fabio
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Operator splitting and approximate factorization for taxis-diffusion-reaction models [PDF]
, 2000 In this paper we consider the numerical solution of 2D systems of certain types of taxis-diffusion-reaction equations from mathematical biology. By spatial discretization these PDE systems are approximated by systems of positive, nonlinear ODEs (Method ...
Gerisch, A. +2 more
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An operator-induced conformational change in the C-terminal domain of the λ repressor [PDF]
, 1992 4,4'-bis(1-anilino-8-naphthalenesulfonic acid (Bis-ANS), an environment-sensitive fluorescent probe for hydrophobic region of proteins, binds specifically to the C-terminal domain of λ repressor.
Bhattacharyya, B. +5 more
core +2 more sources
A review of fractional order epidemic models for life sciences problems: Past, present and future
Alexandria Engineering JournalBoth mathematics and science exhibit a reciprocally advantageous and close relationship. The undeniable significance of mathematics in diverse scientific fields, including electrical engineering, physics, biology, and medicine, is beyond dispute.
Kottakkaran Sooppy Nisar +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
B12-based photoreceptors: from structure and function to applications in optogenetics and synthetic biology [PDF]
, 2019 Vitamin B12-based photoreceptor proteins sense ultraviolet (UV), blue or green light using 5´-deoxyadenosylcobalamin (AdoCbl). The prototype of this widespread bacterial photoreceptor family, CarH, controls light-dependent gene expression in ...
Pérez-Castaño, Ricardo +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source