Results 131 to 140 of about 1,844,598 (293)
JayaX: Jaya algorithm with xor operator for binary optimization
, 2019 Jaya is a population-based heuristic optimization algorithm proposed for solving constrained and unconstrained optimization problems. The peculiar distinct feature of Jaya from the other population-based algorithms is that it updates the positions of ...
Aslan, Murat +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Pragmatic turn in biology: From biological molecules to genetic content operators
World Journal of Biological Chemistry, 2014 Erwin Schrödinger's question "What is life?" received the answer for decades of "physics + chemistry". The concepts of Alain Turing and John von Neumann introduced a third term: "information". This led to the understanding of nucleic acid sequences as a natural code. Manfred Eigen adapted the concept of Hammings "sequence space".
openaire +2 more sources
Fourier integrals and a new representation of Maslov's canonical operator near caustics [PDF]
, 2013 We suggest a new representation of Maslov's canonical operator in a neighborhood of the caustics using a special class of coordinate systems (\eikonal coordinates") on Lagrangian ...
Dobrokhotov, Sergey +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Kinetic equation for a gas with attractive forces as a functional equation
Annales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2009 Diffusion problems studied in the time scale comparable with time of particles collision lead to kinetic equations which for step-wise potentials are functional equations in the velocity space.
Ryszard Wojnar
doaj
Computational biology approach to uncover hepatitis C virus helicase operation
World Journal of Gastroenterology, 2014 22 pages, 5 ...
openaire +4 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
2016 national gas forecasting report [PDF]
, 2016 The 2016 NGFR provides insights into the increasingly complex interdependencies between the gas and electricity sectors and the relationship between Australia’s energy demand and growing links to the international gas sector.
Australian Energy Market Operator
core