Results 71 to 80 of about 260,764 (294)

An Evolutionary Algorithm With Heuristic Operator for Detecting Protein Complexes in Protein Interaction Networks With Negative Controls

IEEE Access
Computational biology research faces a formidable challenge in the detection of complexes within protein-protein interaction (PPI) networks, critical for unraveling cellular processes, predicting functions of uncharacterized proteins, and diagnosing ...
Mustafa N. Abbas, Bara'a A. Attea, David Broneske, Gunter Saake   +3 more
doaj   +1 more source

Development and Verification of a Combined Immune- and Metabolism-Related Prognostic Signature for Hepatocellular Carcinoma

Frontiers in Immunology, 2022
Immune escape and metabolic reprogramming are becoming important characteristics of tumor biology, which play critical roles in tumor initiation and progression.
Yuanyuan Guo, Yuanyuan Guo, Jing Yang, Jing Yang, Hua Gao, Xin Tian, Xin Tian, Xiaojian Zhang, Xiaojian Zhang, Quancheng Kan, Quancheng Kan   +10 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Systems Biology Graphical Notation: Process Description language Level 1 Version 2.0

Journal of Integrative Bioinformatics, 2019
The Systems Biology Graphical Notation (SBGN) is an international community effort that aims to standardise the visualisation of pathways and networks for readers with diverse scientific backgrounds as well as to support an efficient and accurate ...
Rougny Adrien, Touré Vasundra, Moodie Stuart, Balaur Irina, Czauderna Tobias, Borlinghaus Hanna, Dogrusoz Ugur, Mazein Alexander, Dräger Andreas, Blinov Michael L., Villéger Alice, Haw Robin, Demir Emek, Mi Huaiyu, Sorokin Anatoly, Schreiber Falk, Luna Augustin   +16 more
doaj   +1 more source

Tetracycline-controlled (TetON) gene expression system for the smut fungus Ustilago maydis

Frontiers in Fungal Biology, 2022
Ustilago maydis is a biotrophic phytopathogenic fungus that causes corn smut disease. As a well-established model system, U. maydis is genetically fully accessible with large omics datasets available and subject to various biological questions ranging ...
Kishor D. Ingole, Nithya Nagarajan, Simon Uhse, Caterina Giannini, Armin Djamei   +4 more
doaj   +1 more source

Modular organisation of interaction networks based on asymptotic dynamics [PDF]

, 2012
This paper investigates questions related to the modularity in discrete models of biological interaction networks. We develop a theoretical framework based on the analysis of their asymptotic dynamics.
Delaplace, Franck, Klaudel, Hanna, Melliti, Tarek, Sené, Sylvain   +3 more
core   +6 more sources

Novel Analysis of Fuzzy Fractional Emden-Fowler Equations within New Iterative Transform Method

Journal of Function Spaces, 2022
The analytical behavior of fractional differential equations is often puzzling and difficult to predict under uncertainty. It is crucial to develop a robust, extensive, and extremely successful theory to address these problems.
M. Mossa Al-Sawalha, Naila Amir, Rasool Shah, Muhammad Yar   +3 more
doaj   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

HighDimMixedModels.jl: Robust high-dimensional mixed-effects models across omics data.

PLoS Computational Biology
High-dimensional mixed-effects models are an increasingly important form of regression in which the number of covariates rivals or exceeds the number of samples, which are collected in groups or clusters.
Evan Gorstein, Rosa Aghdam, Claudia Solís-Lemus   +2 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source