Results 81 to 90 of about 2,130,795 (350)
Bayesian inversion of a diffusion model with application to biology
Journal of Mathematical Biology, 2021 A common task in experimental sciences is to fit mathematical models to real-world measurements to improve understanding of natural phenomenon (reverse-engineering or inverse modelling).
J. Croix +2 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Boundary value problems for systems of non-degenerate difference-algebraic equations
Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika, 2019 The study of differential-algebraic boundary value problems was initiated in the works of K. Weierstrass, N.N. Luzin and F.R. Gantmacher. Systematic study of differential-algebraic boundary value problems is devoted to the work of S.
Sergey Chuiko +2 more
doaj +1 more source
Pulse-Based Control Using Koopman Operator Under Parametric Uncertainty [PDF]
IEEE Transactions on Automatic Control, 2017 In applications, such as biomedicine and systems/synthetic biology, technical limitations in actuation complicate implementation of time-varying control signals.
Aivar Sootla, D. Ernst
semanticscholar +1 more source
, 2005 We consider a model of spatial spread that has applications in both material science and biology. The classical models are based upon partial differential equations, in particular reaction-diffusion equations. Here the dispersal term is given in terms of
Grinfeld, M. +4 more
core
Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Travelling wave solutions in a negative nonlinear diffusion-reaction model
, 2020 We use a geometric approach to prove the existence of smooth travelling wave solutions of a nonlinear diffusion-reaction equation with logistic kinetics and a convex nonlinear diffusivity function which changes sign twice in our domain of interest.
Li, Yifei +3 more
core +1 more source
Homogenization Model for Aberrant Crypt Foci [PDF]
, 2016 Several explanations can be found in the literature about the origin of colorectal cancer. There is however some agreement on the fact that the carcinogenic process is a result of several genetic mutations of normal cells.
Engquist, Bjorn +3 more
core +2 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source