Results 81 to 90 of about 260,764 (294)
An open-source FACS automation system for high-throughput cell biology.
PLoS ONERecent advances in gene editing are enabling the engineering of cells with an unprecedented level of scale. To capitalize on this opportunity, new methods are needed to accelerate the different steps required to manufacture and handle engineered cells ...
Diane M Wiener +12 more
doaj +1 more source
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
An innovative analytical method utilizing aboodh residual power series for solving the time-fractional newell-whitehead-segel equation [PDF]
Computational Algorithms and Numerical DimensionsIn this study, we use a new method called Abode Residual Power Series Method (ARPSM) to derive the analytical results of the Newell-Whitehead-Siegel equation.
Seyed Edalatpanah, Eisa Abdolmaleki
doaj +1 more source
Control of reaction-diffusion equations on time-evolving manifolds
, 2016 Among the main actors of organism development there are morphogens, which are signaling molecules diffusing in the developing organism and acting on cells to produce local responses. Growth is thus determined by the distribution of such signal. Meanwhile,
Duteil, Nastassia Pouradier +3 more
core +1 more source
Automated High-Throughput Microchannel Assays for Cell Biology: Operational Optimization and Characterization [PDF]
JALA: Journal of the Association for Laboratory Automation, 2010 Screening biological readouts in cell culture are increasing in frequency and throughput. In such assays, cell types may be rare and reagents or compounds may be expensive often resulting in a reduced number of conditions and/or replicates. “Tubeless” microfluidics offers a method to reduce this burden, as has been previously shown. In addition the In-
David J. Beebe +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Dispersion operators and resistant second-order functional data analysis [PDF]
, 2017 Inferences related to the second-order properties of functional data, as expressed by covariance structure, can become unreliable when the data are non-Gaussian or contain unusual observations. In the functional setting, it is often difficult to identify
Kraus, David, Panaretos, Victor M.
core
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Toll Based Measures for Dynamical Graphs [PDF]
, 2007 Biological networks are one of the most studied object in computational biology. Several methods have been developed for studying qualitative properties of biological networks.
Bourdon, Jérémie, Eveillard, Damien
core +2 more sources
, 2016 This work is to develop a general framework, namely analytical iterative reconstruction (AIR) method, to incorporate analytical reconstruction (AR) method into iterative reconstruction (IR) method, for enhanced CT image quality and reconstruction ...
Gao, Hao
core +1 more source