Results 81 to 90 of about 277,157 (310)

A source inverse problem for the pseudo–parabolic equation with the fractional Sturm–Liouville operator

Қарағанды университетінің хабаршысы. Математика сериясы, 2020
A class of inverse problems for restoring the right-hand side of the pseudo-parabolic equation with one fractional Sturm–Liouville operator is considered.
D. Serikbaev, N. Tokmagambetov
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

HighDimMixedModels.jl: Robust high-dimensional mixed-effects models across omics data.

PLoS Computational Biology
High-dimensional mixed-effects models are an increasingly important form of regression in which the number of covariates rivals or exceeds the number of samples, which are collected in groups or clusters.
Evan Gorstein, Rosa Aghdam, Claudia Solís-Lemus   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Systems Biology Graphical Notation: Process Description language Level 1 Version 2.0

Journal of Integrative Bioinformatics, 2019
The Systems Biology Graphical Notation (SBGN) is an international community effort that aims to standardise the visualisation of pathways and networks for readers with diverse scientific backgrounds as well as to support an efficient and accurate ...
Rougny Adrien, Touré Vasundra, Moodie Stuart, Balaur Irina, Czauderna Tobias, Borlinghaus Hanna, Dogrusoz Ugur, Mazein Alexander, Dräger Andreas, Blinov Michael L., Villéger Alice, Haw Robin, Demir Emek, Mi Huaiyu, Sorokin Anatoly, Schreiber Falk, Luna Augustin   +16 more
doaj   +1 more source

Asymptotic estimates related to an integro differential equation

, 2013
The paper deals with an integrodifferential operator which models numerous phenomena in superconductivity, in biology and in viscoelasticity. Initialboundary value problems with Neumann, Dirichlet and mixed boundary conditions are analyzed. An asymptotic
De Angelis, M.
core  

Stochastic delocalization of finite populations

, 2012
Heterogeneities in environmental conditions often induce corresponding heterogeneities in the distribution of species. In the extreme case of a localized patch of increased growth rates, reproducing populations can become strongly concentrated at the ...
Kimura M, Kimura M, Kolmogorov A N, Lukas Geyrhofer, Lynch M, Oskar Hallatschek, Tunnicliffe V, Whitlock M C, Wolff A   +8 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

An open-source FACS automation system for high-throughput cell biology.

PLoS ONE
Recent advances in gene editing are enabling the engineering of cells with an unprecedented level of scale. To capitalize on this opportunity, new methods are needed to accelerate the different steps required to manufacture and handle engineered cells ...
Diane M Wiener, Emily Huynh, Ilakkiyan Jeyakumar, Sophie Bax, Samia Sama, Joana P Cabrera, Verina Todorova, Madhuri Vangipuram, Shivanshi Vaid, Fumitaka Otsuka, Yoshitsugu Sakai, Manuel D Leonetti, Rafael Gómez-Sjöberg   +12 more
doaj   +1 more source

Automated Platforms in C. elegans Research: Integration of Microfluidics, Robotics, and Artificial Intelligence

Micromachines
Caenorhabditis elegans is one of the most extensively studied model organisms in biology. Its advantageous features, including genetic homology with humans, conservation of disease pathways, transparency, short lifespan, small size and ease of ...
Tasnuva Binte Mahbub, Parsa Safaeian, Salman Sohrabi   +2 more
doaj   +1 more source