Results 51 to 60 of about 108,839 (264)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Boundedly solvable extensions of delay differential operators

Electronic Journal of Differential Equations, 2017
We describe all boundedly solvable extensions of minimal operators generated by first-order linear delay differential operators in Hilbert spaces of vector-functions on finite intervals. Also, we study the structure of spectrum of these extensions.
Bahadir O. Guler, Bulent Yilmaz, Zameddin I. Ismailov   +2 more
doaj  

Exponential Formulas and Lie Algebra Type Star Products

Symmetry, Integrability and Geometry: Methods and Applications, 2012
Given formal differential operators $F_i$ on polynomial algebrain several variables $x_1,...,x_n$, we discuss finding expressions $K_l$ determined by the equation $exp(sum_i x_i F_i)(exp(sum_j q_j x_j)) = exp(sum_l K_l x_l)$ and their applications.
Dragutin Svrtan, Zoran Škoda, Stjepan Meljanac, Stjepan Meljanac, Zoran Škoda, Dragutin Svrtan   +5 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Solvability of multipoint differential operators of first order

Electronic Journal of Differential Equations, 2015
Based on methods of operator theory, we describe all boundedly solvable extensions of the minimal operator generated by a linear multipoint functional differential-operator expression of first order, in a direct sum of Hilbert space of vector ...
Zameddin I. Ismailov, Pembe Ipek
doaj  

Accretive and nonnegative perturbations of an abstract analogy for the operator of the third boundary problem and corresponding variational problems(in Ukrainian) [PDF]

Математичні Студії, 2011
In the paper the role of initial object is played by the positively definite operator L_0 acting in a Hilbert space H. The main object of the investigation is operator L B: It is interpreted as a perturbation of some proper extension of L0. Using methods
H. M. Kachurivska, O. G. Storozh
doaj  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source