Results 61 to 70 of about 3,849,527 (290)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Spectral decomposition of self-adjoint operators in Pontryagin and Krein spaces
We consider a self-adjoint operator acting in a Krein space and possessing an invariant subspace that is maximal nonnegative and decomposes into a direct sum of a uniformly positive (i.e., equivalent to a Hilbert space with respect to the inner ...
V. A. Strauss
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Boundedly solvable extensions of delay differential operators
We describe all boundedly solvable extensions of minimal operators generated by first-order linear delay differential operators in Hilbert spaces of vector-functions on finite intervals. Also, we study the structure of spectrum of these extensions.
Bahadir O. Guler +2 more
doaj
Exponential Formulas and Lie Algebra Type Star Products
Given formal differential operators $F_i$ on polynomial algebrain several variables $x_1,...,x_n$, we discuss finding expressions $K_l$ determined by the equation $exp(sum_i x_i F_i)(exp(sum_j q_j x_j)) = exp(sum_l K_l x_l)$ and their applications.
Dragutin Svrtan +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Completely contractive representations of some doubly generated antisymmetric operator algebras. [PDF]
Contractive weak star continuous representations of the Fourier binest algebra (of Katavolos and Power) are shown to be completely contractive. The proof depends on the approximation of by semicrossed product algebras and on the complete contractivity of
Power, Stephen C.
core +4 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Upper Bounds for the Euclidean Operator Radius and Applications [PDF]
The main aim of the present paper is to establish various sharp upper bounds for the Euclidean operator radius of an n−tuple of bounded linear operators on a Hilbert space.
Dragomir, Sever S
core +3 more sources

