Results 81 to 90 of about 3,849,527 (290)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Operator bases, S-matrices, and their partition functions
Journal of High Energy Physics, 2017 Relativistic quantum systems that admit scattering experiments are quantitatively described by effective field theories, where S-matrix kinematics and symmetry considerations are encoded in the operator spectrum of the EFT.
Brian Henning +3 more
doaj +1 more source
ANALYSIS OF EXPRESSION OPERATIONS
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 1971 The internal mechanisms of expression operations are analysed in view of the variations of flow rate through filter-cake and of the modified consolidation coefficient through consolidated cake, and basic equations for consolidation processes are presented in this paper. Expression operations are classified into three types according to the relations of
SHIRATO, MOMPEI +3 more
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
An integral operator on the classes \(\mathcal{S}^{\ast}(\alpha )\) and \(\mathcal{CVH}(\beta )\)
, 2015 The purpose of this paper is to study some properties related to convexity order and coefficients estimation for a general integral operator. We find the convexity order for this operator, using the analytic functions from the class of starlike functions
Ularu, Nicoleta, Breaz, Nicoleta
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A new eigenvalue problem for the difference operator with nonlocal conditions
Nonlinear Analysis, 2019 In the paper, the spectrum structure of one-dimensional differential operator with nonlocal conditions and of the difference operator, corresponding to it, has been exhaustively investigated.
Mifodijus Sapagovas +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
pFAR plasmids: New Eukaryotic Expression Vectors for Gene Therapy, devoid of Antibiotic Resistance Markers [PDF]
, 2008 Efficient production of eukaryotic expression vectors requires the selection of plasmid-containing bacteria. To avoid the risk of dissemination of antibiotic resistance markers, we developed a new system to produce a family of plasmids Free of Antibiotic
Corinne Marie +5 more
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