Results 111 to 120 of about 1,434,936 (326)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A subordination results for a class of analytic functions defined by q-differential operator

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2020
In this paper, we derive several subordination results and integral means result for certain class of analytic functions defined by means of q-differential operator. Some interesting corollaries and consequences of our results are also considered.
Basem Aref Frasin   +1 more
doaj  

Comparison of Various Means for Operators

open access: yesJournal of Functional Analysis, 1999
Let \(A\), \(B\) be nonnegative Hilbert space operators and let \(T\) be an arbitrary linear bounded operator, all acting on a Hilbert space. The inequality \[ \| A^{1/2} TB^{1/2}\|\leq 1/2\| AT+ TB\|, \] was only recently found in operator theory, in connection with some concrete problems of harmonic analysis, see \textit{R.
Hiai, Fumio, Kosaki, Hideki
openaire   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

On the Riesz Means of Expansion by Riesz Bases Formed by Eigen Functions for the Ordinary Differential Operator of 2mth Order

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
  The aim of this paper is to prove a theorem on the Riesz means of expansions with respect to Riesz bases, which extends the previous results of [1] and [2] on the Schrödinger operator and the ordinary differential operator of 4-th order to the ...
A. A. Aswhad
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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