Results 81 to 90 of about 1,434,936 (326)
A Hybrid k-Means Cuckoo Search Algorithm Applied to the Counterfort Retaining Walls Problem
Mathematics, 2020 The counterfort retaining wall is one of the most frequent structures used in civil engineering. In this structure, optimization of cost and CO2 emissions are important.
José García +2 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Operator functions and the operator harmonic mean [PDF]
Proceedings of the American Mathematical Society, 2019 The objective of this paper is to investigate operator functions by making use of the operator harmonic mean ‘ ! \,!\, ’. For 0 > A ≦ B 0>A\leqq B , we construct a unique pair X X , Y Y such that 0
openaire +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
ANALYSIS OF ELECTROENCEPHALOGRAMS RHYTHMS BY MEANS OF NONLINEAR OPERATOR TEAGER-KAISER
Doklady Belorusskogo gosudarstvennogo universiteta informatiki i radioèlektroniki, 2019 The results of the development and application of methods for solution of applied tasks of analysis of the rhythmic activity of the electroencephalogram based on the nonlinear operator.
A. O. Kozmidiadi, A. P. Kluev
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Abstract and Applied Analysis, 2013 We study almost everywhere convergence for Riesz means related to Schrödinger operator with constant magnetic fields. Through researching the weighted norm estimates for the maximal operator with power-weight functions, we obtain the desired result ...
Liurui Deng, Bolin Ma
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source