Results 61 to 70 of about 20,529 (316)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Norm Estimates for Solutions of Polynomial Operator Equations

Journal of Mathematics, 2015
We consider the equations ∑k=0mcm-kAkXBk=C and ∑k=0mcm-kAkXBm-k=C, where ck∈C  (k=1,…,m), c0=1, A,B,C are given linear bounded operators in a Banach space and X is to be found. Representations of solutions are derived.
Michael Gil’
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Norm Attaining Operators and Pseudospectrum [PDF]

Integral Equations and Operator Theory, 2009
It is shown that if $11$, the operator $I+T$ attains its norm. A reflexive Banach space $X$ and a bounded rank one operator $T$ on $X$ are constructed such that $\|I+T\|>1$ and $I+T$ does not attain its norm.
openaire   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

ON THE NORM ATTAINING OPERATORS [PDF]

Korean Journal of Mathematics, 2012
Summary: In this paper, we show the norm attaining paranormal operators have a nontrivial invariant subspace. Also, we show the norm attaining quadratically hyponormal weighted shift is subnormal.
openaire   +1 more source

Operator space tensor norms

, 2023
The use of a tensor product perspective has enriched functional analysis and other important areas of mathematics and physics. The context of operator spaces is clearly no exception. The aim of this manuscript is to kick off the development of a systematic theory of tensor products and tensor norms for operator spaces and its interplay with their ...
Chávez-Domínguez, Alejandro, Dimant, Verónica, Galicer, Daniel   +2 more
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Learning neural operators on Riemannian manifolds

National Science Open
Learning mappings between functions (operators) defined on complex computational domains is a common theoretical challenge in machine learning. Existing operator learning methods mainly focus on regular computational domains, and have many components ...
Chen Gengxiang, Liu Xu, Meng Qinglu, Chen Lu, Liu Changqing, Li Yingguang   +5 more
doaj   +1 more source

Norm estimates for operators in norm-attainable C*-algebras

European Journal of Mathematics and Applications, 2023
Norm estimates for various types of Banach algebra operators have been studied over decades with interesting results obtained. However, it still remains an open problem to determine the norm of an operator in a general Banach space setting. In this note,
Sabasi Omaoro, Benard Okelo, Omolo Ongati   +2 more
doaj