Results 71 to 80 of about 25,259 (306)
Linear Operator Inequality and Null Controllability with Vanishing Energy for Unbounded Control Systems [PDF]
, 2013 We consider a linear boundary or point control system on a Hilbert space $H$ which is null controllable at some time $T_0 >0$. To every initial state $ y_0 \in H$ we associate the minimal ``energy'' needed to transfer $ y_0 $ to $ 0 $ in a time $ T \ge ...
Zabczyk, J. +7 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
New versions of refinements and reverses of Young-type inequalities with the Kantorovich constant
Special Matrices, 2023 Recently, some Young-type inequalities have been promoted. The purpose of this article is to give further refinements and reverses to them with Kantorovich constants.
Rashid Mohammad H. M., Bani-Ahmad Feras
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Norm Estimates for Solutions of Polynomial Operator Equations
Journal of Mathematics, 2015 We consider the equations ∑k=0mcm-kAkXBk=C and ∑k=0mcm-kAkXBm-k=C, where ck∈C (k=1,…,m), c0=1, A,B,C are given linear bounded operators in a Banach space and X is to be found. Representations of solutions are derived.
Michael Gil’
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Poincaré Inequalities for Composition Operators with Lφ-Norm
Abstract and Applied Analysis, 2014 We establish the Poincaré-type inequalities for the composition of the homotopy operator, exterior derivative operator, and the projection operator with Lφ-norm applied to the nonhomogeneous A-harmonic equation in Lφ(Ω)-averaging domains.
Ru Fang
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Norms of Hankel Operators on a Bidisc [PDF]
Proceedings of the American Mathematical Society, 1990 In the Hardy space on the bidisc T 2 {T^2}
openaire +2 more sources