Results 81 to 90 of about 773,316 (284)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

On the Norm of Certain Weighted Composition Operators on the Hardy Space

open access: yesAbstract and Applied Analysis, 2009
We obtain a representation for the norm of certain compact weighted composition operator 𝐶𝜓,𝜑 on the Hardy space 𝐻2, whenever 𝜑(𝑧)=𝑎𝑧+𝑏 and 𝜓(𝑧)=𝑎𝑧−𝑏. We also estimate the norm and essential norm of a class of noncompact weighted composition operators ...
M. Haji Shaabani, B. Khani Robati
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Norms of Hankel Operators on a Bidisc [PDF]

open access: yesProceedings of the American Mathematical Society, 1990
In the Hardy space on the bidisc T 2 {T^2}
openaire   +2 more sources

Density and dentability in norm-attainable classes

open access: yesScientific African
We establish the norm-denseness of the norm-attainable class NA(H) in the Banach algebra B(H), which consists of all bounded linear operators on a complex Hilbert space H. Specifically, for every O∈NA(H) and each ϵ>0, there exists O′∈B(H) such that ‖O−O′‖
Joseph Owuor   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A natural space of functions for the Ruelle operator theorem [PDF]

open access: yes, 2007
We study a new space, $R(X)$, of real-valued continuous functions on the space $X$ of sequences of zeros and ones. We show exactly when the Ruelle operator theorem holds for such functions.
Walters, Peter
core   +1 more source

Maximum norm a posteriori error estimation for parabolic problems using elliptic reconstructions [PDF]

open access: yes, 2013
A semilinear second-order parabolic equation is considered in a regular and a singularly perturbed regime. For this equation, we give computable a posteriori error estimates in the maximum norm.
Linss, Torsten, Kopteva, Natalia
core   +2 more sources

Home - About - Disclaimer - Privacy