Results 91 to 100 of about 443,680 (282)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Operator-Valued Norms

open access: yes, 2007
We introduce two kinds of operator-valued norms. One of them is an $L(H)$-valued norm. The other one is an $L(C(K))$-valued norm. We characterize the completeness with respect to a bounded $L(H)$-valued norm. Furthermore, for a given Banach space $\textbf{B}$, we provide an $L(C(K))$-valued norm on $\textbf{B}$.
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

More power vector bounds for operator pairs in Hilbert spaces with applications

open access: yesJournal of Inequalities and Applications
This paper investigates power vector inequalities for bounded linear operator pairs ( B , C ) $(B,C)$ in a Hilbert space H $\mathcal{H}$ . By leveraging vector inequalities derived by the second author for inner products and norms, we establish various ...
Najla Altwaijry   +2 more
doaj   +1 more source

Recent Advances in Lp-Theory of Homotopy Operator on Differential Forms

open access: yesAbstract and Applied Analysis, 2014
The purpose of this survey paper is to present an up-to-date account of the recent advances made in the study of Lp-theory of the homotopy operator applied to differential forms.
Shusen Ding, Peilin Shi, Yong Wang
doaj   +1 more source

Multiplication Operators on Weighted Banach Spaces of a Tree

open access: yes, 2015
We study multiplication operators on the weighted Banach spaces of an infinite tree. We characterize the bounded and the compact operators, as well as determine the operator norm.
Allen, Robert F., Craig, Isaac M.
core  

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