Results 91 to 100 of about 770,686 (284)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Relations entre Psi_B et quelques représentations temps-fréquence [PDF]
, 2010 Psi_B operator is an energy operator that measures the interactions between two complex signals. In this letter, new properties of Psi_B operator are presented.
BOUDRAA, Abdel-Ouahab
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
More power vector bounds for operator pairs in Hilbert spaces with applications
Journal of Inequalities and ApplicationsThis paper investigates power vector inequalities for bounded linear operator pairs ( B , C ) $(B,C)$ in a Hilbert space H $\mathcal{H}$ . By leveraging vector inequalities derived by the second author for inner products and norms, we establish various ...
Najla Altwaijry +2 more
doaj +1 more source
Multiplication Operators between Lipschitz-Type Spaces on a Tree
International Journal of Mathematics and Mathematical Sciences, 2011 Let ℒ be the space of complex-valued functions 𝑓 on the set of vertices 𝑇 of an infinite tree rooted at 𝑜 such that the difference of the values of 𝑓 at neighboring vertices remains bounded throughout the tree, and let ℒ𝐰 be the set of functions 𝑓∈ℒ such
Robert F. Allen +2 more
doaj +1 more source
A metric approach to limit operators
, 2017 We extend the limit operator machinery of Rabinovich, Roch, and Silbermann from Z^N to (bounded geometry, strongly) discrete metric spaces. We do not assume the presence of any group structure or action on our metric spaces.
Spakula, Jan, Willett, Rufus
core +1 more source