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The relative value of operon predictions [PDF]
For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combination of) the following five criteria: (i) intergenic distance, (ii ...
Rutger W W Brouwer +2 more
exaly +2 more sources
Glucomannan utilization operon ofBacillus subtilis [PDF]
This study characterizes the glucomannan utilization operon (gmuBACDREFG, formerly ydhMNOPQRST) of Bacillus subtilis. Transcription of the operon is induced by konjac glucomannan and requires the last mannanase gene (gmuG).
Yoshito Sadaie
exaly +1 more source
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Proteins: Structure, Function, and Bioinformatics, 2006
AbstractOperons are clusters of genes that are transcribed as a single message, and regulated by the same gene expression machinery. They are found primarily in prokaryotic genomes. Because genes in the same operon are likely to have related functions, identification of the operon structure is potentially useful for assigning gene function.
Yongpan, Yan, John, Moult
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AbstractOperons are clusters of genes that are transcribed as a single message, and regulated by the same gene expression machinery. They are found primarily in prokaryotic genomes. Because genes in the same operon are likely to have related functions, identification of the operon structure is potentially useful for assigning gene function.
Yongpan, Yan, John, Moult
openaire +2 more sources
Microbial & Comparative Genomics, 1998
To achieve coordinate gene regulation, yeast (Saccharomyces cerevisiae) appears to have exploited two distinct multifunction "operon" schemas: one, by concatenating originally separate functional domains into single polypeptides, and two, by linking opposite strand genes through common promoter elements.
X, Zhang, T F, Smith
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To achieve coordinate gene regulation, yeast (Saccharomyces cerevisiae) appears to have exploited two distinct multifunction "operon" schemas: one, by concatenating originally separate functional domains into single polypeptides, and two, by linking opposite strand genes through common promoter elements.
X, Zhang, T F, Smith
openaire +2 more sources
2003
The major factor determining the different pathogenicities of meningococci and their close relatives, the gonococci, is the polysaccharide capsule. The capsule protects meningococci from complement attack and phagocytosis and is indispensable for systemic spread of the bacteria during sepsis and meningitis (1-5).
U, Vogel, H, Claus, M, Frosch
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The major factor determining the different pathogenicities of meningococci and their close relatives, the gonococci, is the polysaccharide capsule. The capsule protects meningococci from complement attack and phagocytosis and is indispensable for systemic spread of the bacteria during sepsis and meningitis (1-5).
U, Vogel, H, Claus, M, Frosch
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Annual Review of Genetics, 1972
Simple observation of living organisms allows one to conclude that the entire genetic potential of any given cell is never expressed at any given moment. In bacteria this phenomenon is termed genetic adaptation and it occurs in two apparently contradictory ways. The synthesis of enzymes responsible for a catabolic process generally appears to be turned
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Simple observation of living organisms allows one to conclude that the entire genetic potential of any given cell is never expressed at any given moment. In bacteria this phenomenon is termed genetic adaptation and it occurs in two apparently contradictory ways. The synthesis of enzymes responsible for a catabolic process generally appears to be turned
openaire +2 more sources
2013
The biosynthesis of histidine has been studied extensively in Salmonella enterica and Escherichia coli. In these enterobacteria, a single operon composed of eight adjacent genes encodes the complete set of histidine biosynthetic enzymes. Three (hisD, hisNB,andhisIE) of the eight genes encode bifunctional enzymes, while two (hisH and hisF) encode a ...
P. Alifano, FANI, RENATO
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The biosynthesis of histidine has been studied extensively in Salmonella enterica and Escherichia coli. In these enterobacteria, a single operon composed of eight adjacent genes encodes the complete set of histidine biosynthetic enzymes. Three (hisD, hisNB,andhisIE) of the eight genes encode bifunctional enzymes, while two (hisH and hisF) encode a ...
P. Alifano, FANI, RENATO
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The Origin and Evolution of Operons: The Piecewise Building of the Proteobacterial Histidine Operon
Journal of Molecular Evolution, 2005The structure and organization of 470 histidine biosynthetic genes from 47 different proteobacteria were combined with phylogenetic inference to investigate the mechanisms responsible for assembly of the his pathway and the origin of his operons. Data obtained in this work showed that a wide variety of different organization strategies of his gene ...
FANI, RENATO, M. Brilli, P. Liò
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Trends in Biochemical Sciences, 1991
Ribosomal RNA (rRNA) operons of the archaea reflect both the unity and the diversity of this third primary taxon. They have proven to be a rich source of both molecular biological and phylogenetic information.
Garrett, Roger A. +4 more
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Ribosomal RNA (rRNA) operons of the archaea reflect both the unity and the diversity of this third primary taxon. They have proven to be a rich source of both molecular biological and phylogenetic information.
Garrett, Roger A. +4 more
openaire +2 more sources
Operon identifier: Identification of operon structures in the whole genome
Proceedings II of the 28st Conference STUDENT EEICT 2022: Selected papers., 2022Currently, operon prediction is based on the distance of neighboring genes on the functional relationships of their products that encode proteins in a given nucleotide sequence, or on ORF distances. This study deals with the design of a new function that detects operon structures based on information from gene expression or alternatively in combination
Nejezchlebová, Julie +1 more
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