Results 11 to 20 of about 116,281 (318)

The life-cycle of operons. [PDF]

open access: yesPLoS Genetics, 2006
Operons are a major feature of all prokaryotic genomes, but how and why operon structures vary is not well understood. To elucidate the life-cycle of operons, we compared gene order between Escherichia coli K12 and its relatives and identified the ...
Morgan N Price, Adam P Arkin, Eric J Alm
doaj   +6 more sources

Operons [PDF]

open access: yesCellular and Molecular Life Sciences, 2009
Operons (clusters of co-regulated genes with related functions) are common features of bacterial genomes. More recently, functional gene clustering has been reported in eukaryotes, from yeasts to filamentous fungi, plants, and animals. Gene clusters can consist of paralogous genes that have most likely arisen by gene duplication. However, there are now
Ben Field, Anne Osbourn
openaire   +3 more sources

Genome Mining Enabled by Biosynthetic Characterization Uncovers a Class of Benzoxazolinate‐Containing Natural Products in Diverse Bacteria

open access: yesAngewandte Chemie, Volume 134, Issue 51, December 19, 2022., 2022
Benzoxazolinate is a rare bis‐heterocyclic moiety that interacts with proteins and DNA. It was found that a putative acyl AMP‐ligase mediates the last cyclization step to afford benzoxazolinate. The enzyme was then used as a probe for genome mining, which led to the discovery of a new class of benzoxazolinate‐containing compounds in diverse bacteria ...
Yi‐Ming Shi   +12 more
wiley   +2 more sources

Modeling operon dynamics: the tryptophan and lactose operons as paradigms [PDF]

open access: yesComptes Rendus. Biologies, 2004
Understanding the regulation of gene control networks and their ensuing dynamics will be a critical component in the understanding of the mountain of genomic data being currently collected. This paper reviews recent mathematical modeling work on the tryptophan and lactose operons which are, respectively, the classical paradigms for repressible and ...
Yildirim, N, Mackey, MC, Santillan, M
openaire   +3 more sources

Downy mildew resistance and genetic variability in a wild rocket germplasm collection

open access: yesAgronomy Journal, Volume 114, Issue 6, Page 3083-3095, November/December 2022., 2022
Abstract One hundred accessions of a “core collection” of Diplotaxis tenuifolia (L.) DC. and Eruca spp. were screened at seedling stage for resistance to downy mildew. Accessions tested at the seedling stage were assigned to 0–6 interaction phenotypes.
Paula S. Coelho   +5 more
wiley   +1 more source

Evaluation of Biofilm Formation and Presence of Genes in Clinical Isolates [PDF]

open access: yesOsong Public Health and Research Perspectives, 2018
Objectives Biofilm formation is one of the important features of Staphylococcus epidermidis, particularly in nosocomial infections. We aimed to investigate the biofilm production by phenotypic methods and the presence of ica genes in S epidermidis ...
Maryam Kord   +5 more
doaj   +1 more source

The Exploration of Novel Regulatory Relationships Drives Haloarchaeal Operon-Like Structural Dynamics over Short Evolutionary Distances

open access: yesMicroorganisms, 2020
Operons are a dominant feature of bacterial and archaeal genome organization. Numerous investigations have related aspects of operon structure to operon function, making operons exemplars for studies aimed at deciphering Nature’s design principles for ...
Phillip Seitzer   +3 more
doaj   +1 more source

Operon Prediction Model Based on Markov Clustering Algorithm [PDF]

open access: yesInternational Journal Bioautomation, 2019
There are many operon prediction models, but few methods can be applied to the operon prediction of new sequencing species effectively. In this paper, an operon prediction model based on Markov clustering algorithm is proposed.
Zhenmei Zhang, Yongquan Liang
doaj   +1 more source

Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors

open access: yesmSphere, 2020
Copper is broadly toxic to bacteria. As such, bacteria have evolved specialized copper export systems (cop operons) often consisting of a DNA-binding/copper-responsive regulator (which can be a repressor or activator), a copper chaperone, and a copper ...
Henrik O’Brien   +5 more
doaj   +1 more source

The mbo operon is specific and essential for biosynthesis of mangotoxin in Pseudomonas syringae. [PDF]

open access: yesPLoS ONE, 2012
Mangotoxin is an antimetabolite toxin produced by certain Pseudomonas syringae pv. syringae strains. This toxin is an oligopeptide that inhibits ornithine N-acetyl transferase, a key enzyme in the biosynthesis of ornithine and arginine.
Víctor J Carrión   +4 more
doaj   +1 more source

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