Results 41 to 50 of about 116,281 (318)
Science, 2011 What is the operon, whose 50th anniversary is being celebrated this week? The word heralded the discovery of how genes are turned on and off, and it launched the now-immense field of gene regulation. The idea was born in André Lwoff's laboratory at the Institut Pasteur.
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Elucidation of Directionality for Co-Expressed Genes: Predicting Intra-Operon Termination Sites [PDF]
Bioinformatics 22(2):209-214 (2006), 2005 We present a novel framework for inferring regulatory and sequence-level information from gene co-expression networks. The key idea of our methodology is the systematic integration of network inference and network topological analysis approaches for uncovering biological insights.
arxiv +1 more source
Nature, 1997 The Iac Operon: A Short History of a Genetic Paradigm by Benno Muller-Hill Walter de Gruyter:1996. Pp. 207.
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Journal of Basic Microbiology, Volume 63, Issue 1, Page 51-63, January 2023., 2023 Abstract Pyocyanin is a phenazine with redox activity produced by Pseudomonas aeruginosa that is harmful to other bacteria and eukaryotic organisms by generating reactive oxygen species. Gene regulation of pyocyanin synthesis has been addressed in the PAO1 and PA14 strains and involves the three‐quorum sensing systems Las, Rhl, and Pqs; the regulators ...
Luis F. Montelongo‐Martínez +7 more
wiley +1 more source
Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state. [PDF]
PLoS Computational Biology, 2018 Within an isogenic population, even in the same extracellular environment, individual cells can exhibit various phenotypic states. The exact role of stochastic gene-state switching regulating the transition among these phenotypic states in a single cell ...
Hao Ge +3 more
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Nature New Biology, 1971 The Lactose Operon. Edited by Jonathan R. Beckwith David Zipser. Pp. ix+437. (Cold Spring Harbor Laboratory: Cold Spring Harbor, New York, 1970.) $12.
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Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
BMC Genomics, 2009 Background The repABC plasmid family, which is extensively present within Alphaproteobacteria, and some secondary chromosomes of the Rhizobiales have the particular feature that all the elements involved in replication and partitioning reside within one ...
Cevallos Miguel A +3 more
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BMC Microbiology, 2022 Background Silver ions have potent broad-spectrum antimicrobial activity and are widely incorporated into a variety of products to limit bacterial growth.
Charlotte A. Woolley +2 more
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Operon and non-operon gene clusters in the C. elegans genome [PDF]
WormBook, 2014 Nearly 15% of the ~20,000 C. elegans genes are contained in operons, multigene clusters controlled by a single promoter. The vast majority of these are of a type where the genes in the cluster are ~100 bp apart and the pre-mRNA is processed by 3' end formation accompanied by trans-splicing.
Thomas Blumenthal +2 more
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