"Live high-train low" induced changes in hemoglobin mass and the erythropoietin-erythroferrone-hepcidin axis in female endurance athletes. [PDF]
Abstract The effects of a 21‐day live high‐train low (LHTL) on hemoglobin mass (Hbmass) and iron demand including the erythropoietin (EPO)‐erythroferrone (ERFE)‐hepcidin axis and routine iron markers were investigated. Fifteen female endurance athletes completed either 21‐day LHTL in normobaric hypoxia (2500 m, ~18 h·day−1) (INT, n = 8) or lived and ...
Kuorelahti T +5 more
europepmc +2 more sources
Metabolic signature of short-term low energy availability. [PDF]
Abstract Exposure to low energy availability (LEA) can potentially detrimentally affect athletes' health and performance. Timely identification is crucial, yet its detection is often delayed until severe symptoms emerge. Our objective was to identify characteristic differences in the serum metabolome as potential early LEA biomarkers.
Nusser V +7 more
europepmc +2 more sources
Short- and Long-Term Effect of Multidomain Lifestyle Intervention on Frailty: Post Hoc Analysis of an RCT. [PDF]
A Sankey diagram illustrating the flow of participants from baseline frailty status to each follow‐up assessment. Data represents numbers of participants observed in each group. ABSTRACT Background The prevalence of frailty is increasing as the population ages. Lifestyle interventions have shown potential in frailty prevention.
Pöyhönen J +11 more
europepmc +2 more sources
Associations between androgen levels and endurance training-induced changes in body composition and physical performance in premenopausal females. [PDF]
Abstract We investigated whether a moderate‐intensity continuous training (MICT) for two menstrual/contraceptive cycles (~8 weeks) alters endogenous androgen concentrations in premenopausal females, and whether baseline androgen concentrations or their changes from baseline to post‐intervention are associated with adaptations in body composition and ...
Salmi VM +5 more
europepmc +2 more sources
Postural Control as a Risk Factor for Noncontact Anterior Cruciate Ligament Injury in Youth Female Basketball and Floorball Athletes. [PDF]
ABSTRACT The aim of this study was to investigate whether postural control was associated with an increased risk of future noncontact ACL injury in youth female basketball and floorball athletes. Data collection on 189 youth female basketball and floorball athletes was performed during a 3‐year period.
Olli K +7 more
europepmc +2 more sources
The Impact of Complement Factor H-Related Protein Gene Deletions on Kidney Transplantation. [PDF]
In this study, we found that rs7542235 allele G tags a deletion of the CFHR1 gene. We also found that rs6677604 allele A tags a deletion of the whole CFHR3–1 locus. The plasma proteomics studies show that both variants are associated with an altered expression of FH/FHR proteins thus revealing a novel level of intricate regulation of the complement ...
Markkinen S +6 more
europepmc +2 more sources
Long-term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores. [PDF]
FinnGen data of 213 942 women was utilized in order to investigate the risk of cardiovascular disease in women with and without hypertensive disorders of pregnancy and with diverse genetic risks for cardiovascular disease and preeclampsia measured with polygenic risk scores.
Kivioja A +8 more
europepmc +2 more sources
Effects of fractional inspired O<sub>2</sub> on the O<sub>2</sub> pathway during submaximal and maximal exercise in male endurance athletes. [PDF]
Abstract We utilized non‐invasive methods and novel computational approaches to examine the effects of acutely varying fractional inspired O2 (FIO2) on convective and diffusive steps of O2 transport and muscle tissue (de)oxygenation during incremental cycling to exhaustion in 10 Tier 3 and 4 endurance athletes breathing either 0.152, 0.209, or 0.298 ...
Lehtonen E +4 more
europepmc +2 more sources
Diatom and microarthropod communities of three airfields in Estonia – Their differences and similarities and possible linkages to airfield properties [PDF]
Even though airfields, which are often anthropologically modified natural areas, are continuously influenced by human activities, their soils are still dynamic ecosystems containing various habitats for microscopic groups of organisms which are
Koff, Tiiu +6 more
core +2 more sources
Etäpedagogiikan jäsennyksiä suomalaisessa varhaiskasvatuksessa COVID-19 pandemian alkaessa
Tässä tutkimuksessa tarkastellaan ensimmäisen korona-aallon aikana järjestettyä etäopetusta varhaiskasvatuksessa ja sen pedagogisia haasteita. Opetus- ja kasvatuspalvelut pyrittiin mahdollistamaan, kun Suomi sulkeutui koronan vuoksi huhtikuussa 2020 ...
Jonna Kangas, Hanna Niinistö
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