Results 31 to 40 of about 150 (116)

Survey of Network‐Based Approaches to Research of Cardiovascular Diseases

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Cardiovascular diseases (CVDs) are the leading health problem worldwide. Investigating causes and mechanisms of CVDs calls for an integrative approach that would take into account its complex etiology. Biological networks generated from available data on biomolecular interactions are an excellent platform for understanding interconnectedness of all ...
Anida Sarajlić, Nataša Pržulj, Altaf-Ul- Amin   +2 more
wiley   +1 more source

Vitexicarpin Acts as a Novel Angiogenesis Inhibitor and Its Target Network

Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
Vitexicarpin (VIT) isolated from the fruits of Vitex rotundifolia has shown antitumor, anti‐inflammatory, and immunoregulatory properties. This work is designed to evaluate the antiangiogenic effects of VIT and address the underlying action mechanism of VIT by a network pharmacology approach.
Bo Zhang, Lu Liu, Shiwen Zhao, Xu Wang, Liyang Liu, Shao Li, Weidong Zhang   +6 more
wiley   +1 more source

A Systems Biology‐Based Investigation into the Pharmacological Mechanisms of Wu Tou Tang Acting on Rheumatoid Arthritis by Integrating Network Analysis

Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
Aim. To investigate pharmacological mechanisms of Wu Tou Tang acting on rheumatoid arthritis (RA) by integrating network analysis at a system level. Methods and Results. Drug similarity search tool in Therapeutic Targets Database was used to screen 153 drugs with similar structures to compositive compounds of each ingredient in Wu Tou Tang and to ...
Yanqiong Zhang, Danhua Wang, Shufang Tan, Haiyu Xu, Chunfang Liu, Na Lin, Aiping Lu   +6 more
wiley   +1 more source

Ophidian accident in horses in the Amazon Biome, Pará, Brazil [PDF]

Pesquisa Veterinária Brasileira
: Bothrops atrox is the most common viper in the Amazon, and its venom causes local and systemic changes. This report describes the clinicopathological and laboratory findings of ophidism due to Bothrops in six horses in Pará, Brazil.
Analiel Serruya, Cinthia T.A. Lopes, Natália S.S. Silveira, Camila C. Barbosa, Paulo S.C. Costa, Marcos D. Duarte, Karinny F. Campos, José D. Barbosa   +7 more
doaj   +1 more source

Identification of Putative Ortholog Gene Blocks Involved in Gestant and Lactating Mammary Gland Development: A Rodent Cross‐Species Microarray Transcriptomics Approach

International Journal of Genomics, Volume 2013, Issue 1, 2013., 2013
The mammary gland (MG) undergoes functional and metabolic changes during the transition from pregnancy to lactation, possibly by regulation of conserved genes. The objective was to elucidate orthologous genes, chromosome clusters and putative conserved transcriptional modules during MG development.
Maricela Rodríguez-Cruz, Ramón M. Coral-Vázquez, Gabriel Hernández-Stengele, Raúl Sánchez, Emmanuel Salazar, Fausto Sanchez-Muñoz, Sergio Encarnación-Guevara, Jorge Ramírez-Salcedo, Elena Pasyukova   +8 more
wiley   +1 more source

The deadliest snake according to ethnobiological perception of the population of the Alto Juruá region, western Brazilian Amazonia

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: We examined the ethnobiological perception of the population of the Alto Juruá region about different snake species, in terms of their dangerousness and manifestations of envenomation.
Jessyca Lima da Silva, Ageane Mota da Siva, Gardênia Lima Gurgel do Amaral, Givanildo Pereira Ortega, Wuelton Marcelo Monteiro, Paulo Sérgio Bernarde   +5 more
doaj   +1 more source

Navigating Traditional Chinese Medicine Network Pharmacology and Computational Tools

Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
The concept of “network target” has ushered in a new era in the field of traditional Chinese medicine (TCM). As a new research approach, network pharmacology is based on the analysis of network models and systems biology. Taking advantage of advancements in systems biology, a high degree of integration data analysis strategy and interpretable ...
Ming Yang, Jia-Lei Chen, Li-Wen Xu, Guang Ji, Ai-ping Lu   +4 more
wiley   +1 more source

Facilitating HIV testing, care and treatment for orphans and vulnerable children aged five years and younger through community‐based early childhood development playcentres in rural Zimbabwe

Journal of the International AIDS Society, Volume 15, Issue S2, July 2012., 2012
Introduction Early diagnosis of children living with HIV is a prerequisite for accessing timely paediatric HIV care and treatment services and for optimizing treatment outcomes. Testing of HIV‐exposed infants at 6 weeks and later is part of the national prevention of mother to child transmission (PMTCT) of HIV programme in Zimbabwe, but many ...
Diana Patel, Priscilla Matyanga, Tichaona Nyamundaya, Delia Chimedza, Karen Webb, Barbara Engelsmann   +5 more
wiley   +1 more source

Perfil epidemiológico de acidentes ofídicos do Estado do Amapá Epidemiological profile of snake poisoning accidents in the State of Amapá

Revista da Sociedade Brasileira de Medicina Tropical, 2009
O presente trabalho apresenta o perfil epidemiológico dos acidentes ofídicos notificados junto à Secretaria do Estado de Saúde do Estado do Amapá. Para isso, foram analisadas 909 fichas durante o período de 2003 a 2006.
Ana Cristina Silva Ferreira Lima, Carlos Eduardo Costa Campos, José Renato Ribeiro   +2 more
doaj   +1 more source

Popular names for bushmaster (Lachesis muta) and lancehead (Bothrops atrox) snakes in the Alto Juruá region: repercussions for clinical-epidemiological diagnosis and surveillance

Revista da Sociedade Brasileira de Medicina Tropical, 2019
INTRODUCTION: The popular names “surucucu” and “jararaca” have been used in literature for Lachesis muta and Bothrops atrox snakes, respectively.
Ageane Mota da Siva, Wuelton Marcelo Monteiro, Paulo Sérgio Bernarde   +2 more
doaj   +1 more source