Results 191 to 200 of about 36,131 (273)
An injectable CNC–PNIPAM hydrogel is developed for intrauterine co‐delivery of levonorgestrel and botropase. This platform reprograms uterine natural killer cells toward an immune–tolerant phenotype and enhances endometrial receptivity marker expression. The results demonstrate a promising strategy to counteract endometriosis–associated infertility and
Zhou Liang +9 more
wiley +1 more source
Hyaluronic acid modified MPEG-b-PAE block copolymer aqueous micelles for efficient ophthalmic drug delivery of hydrophobic genistein. [PDF]
Li C +5 more
europepmc +1 more source
The World Health Organization Model Essential Medicines List and African national essential medicines lists (EMLs) detail drugs intended to be consistently available within national health systems, thereby supporting clinicians and pharmacists in making evidence‐based treatment decisions.
Tinashe A. Mazhindu +5 more
wiley +1 more source
Short‐term topical ocular steroids and NSAIDs did not result in statistically significant gastrointestinal bleeding or histopathological injury in healthy rats. Limited faecal occult blood positivity was observed in some steroid‐treated animals but was not accompanied by macroscopic or microscopic evidence of mucosal damage .
Harun Cinar +4 more
wiley +1 more source
Methodological Challenges for Ablation of BMPR1A in Hypothalamic Tanycytes—A Cautionary Tale
Two strategies were used to target BMPR1A in adult hypothalamic tanycytes: (1) inducible Rax‐CreERT2 and (2) AAV‐Dio2‐iCre–mediated recombination. Although robust expression of reporter fluorescence and recombination gel analysis confirmed Cre activity in both models, BMPR1A expression was not reduced in targeted tanycytes.
Tianyi Tao +3 more
wiley +1 more source
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown +7 more
wiley +1 more source
Contact lenses : clinical evaluation, associated challenges and perspectives [PDF]
Farandos +14 more
core +1 more source
Fucoidan: An Update on Function, Role in Human Health and Applications
Fucoidan is a promising bioactive compound with anti‐inflammatory, anticoagulant, anticancer, antioxidant, antiviral, and cardioprotective properties. In addition, thanks to its epigenetic potential, ability to modulate autophagic mechanisms and possibility adjuvant agent or bioactive component of the drug delivery systems, fucoidan is a promising ...
Sharon Critelli, Marilena Celano
wiley +1 more source
Chitosan temperature-sensitive gel loaded with drug microspheres has excellent effectiveness, biocompatibility and safety as an ophthalmic drug delivery system. [PDF]
Kong X, Xu W, Zhang C, Kong W.
europepmc +1 more source
\u201cUnexpected in utero exposure to psychotropic medications\u201d [PDF]
Angelini, A +4 more
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