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Functionalized metal-organic framework-based photosensitive hydrogel eye drops for inhibition of corneal neovascularization and promotion of epithelial repair. [PDF]
J NanobiotechnologyMeng C +6 more
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Porcine Corneal Models as Translational Platforms for Innovative Therapies: Current Insights and Future Directions. [PDF]
J Funct BiomaterNápoles P, Faria M, Campos EJ.
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Nanomaterial-based ophthalmic drug delivery
Advanced Drug Delivery Reviews, 2023The low bioavailability and side effects of conventional drugs for eye disease necessitate the development of efficient drug delivery systems. Accompanying the developments of nanofabrication techniques, nanomaterials have been recognized as promising tools to overcome these challenges due to their flexible and programmable properties.
Guocheng Xie +3 more
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Cyclodextrins in ophthalmic drug delivery
Advanced Drug Delivery Reviews, 1999Most ocular diseases are treated by topical drug application in the form of aqueous eye drop solutions. Recent studies have shown that cyclodextrins are useful additives in ophthalmic formulations for increasing the aqueous solubility, aqueous stability and bioavailability of ophthalmic drugs, and to decrease drug irritation.
, Loftssona, , Järvinen
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Ophthalmic drug delivery systems
Drug Development Research, 1984AbstractNew ophthalmic drug delivery systems are curently receiving increased attention, in part because of the expected emergence of new drugs with short biological half‐lives whose usefulness may depend on a more continuous drug supply than eyedrops can provide, but also because of the potential of some delivery systems to reduce the side effects of ...
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Ophthalmic Drug Delivery: New Dimensions
International Journal of Pharmaceutical Sciences and Nanotechnology(IJPSN), 2023The objective of this review is to compile updated scientific information on the conventional and novel approaches to the ocular delivery of medication. Owing to the special features and requirements of a specific site delivery system, there is a need for the refinement of novel drug delivery systems.
RAJAT BUDHORI +5 more
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Colloidal Carriers for Ophthalmic Drug Delivery
Current Drug Targets, 2005To achieve effective drug concentration at the intended site for a sufficient period of time is a requisite desired for many drug formulations. For drugs intended to ocular delivery, its poor bioavailability is due to pre-corneal factors. Most ocular diseases are treated by topical drug application in the form of solution, suspension and ointment ...
Rubiana Mara, Mainardes +6 more
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Ophthalmic drug delivery systems—Recent advances
Progress in Retinal and Eye Research, 1998Eye-drops are the conventional dosage forms that account for 90% of currently accessible ophthalmic formulations. Despite the excellent acceptance by patients, one of the major problems encountered is rapid precorneal drug loss. To improve ocular drug bioavailability, there is a significant effort directed towards new drug delivery systems for ...
C L, Bourlais +5 more
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Microparticulates for Ophthalmic Drug Delivery
Journal of Ocular Pharmacology and Therapeutics, 1994Microparticulates are drug-containing small polymeric particles (erodible, non-erodible or ion-exchange resins) that are suspended in a liquid carrier medium. Upon administration of particle suspension in the eye, the particles reside at the delivery site (cul-de-sac, sub conjunctiva or vitreous cavity) and the drug is released from the particles ...
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