Results 21 to 30 of about 84,715 (301)

Pharmacodynamic approach for proving equivalence of two ophtalmic solutions containing Brimonidine Tartarate 0.2% in healthy volunteers [PDF]

Hospital Pharmacology, 2018
Introduction: Bromonidine tartarate ophthalmic solution (CAS registry-number: 70359- 46-5) is a relatively selective alpha-2 adrenergic agonist, indicated for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular ...
Hristova-Valcheva Ruska, Demircheva-Stojanova Irenna, Petrov Dimitrov Andrey, Gatchev Emil M., Friesinger Yroff Ursula, Richter Hagen Wolfram, Koytchev Krumov Rossen   +6 more
doaj  

In Vitro Evaluation of Combined Commercialized Ophthalmic Solutions Against Acanthamoeba Strains

Pathogens, 2019
Acanthamoeba is a free-living amoebae genus which is present worldwide in natural and artificial environments. These amoebae are clinically important as causative agents of diseases in humans and other animals such as a fatal encephalitis or a sight ...
María Reyes-Batlle, Glorian Mura-Escorche, Ines Sifaoui, Alejandro Otero-Ruiz, Rosalía Alfaro-Sifuentes, Atteneri López-Arencibia, Pedro Rocha-Cabrera, Olfa Chiboub, Aitor Rizo-Liendo, Jonadab Zamora-Herrera, Carlos J. Bethencourt-Estrella, Rubén L. Rodríguez-Expósito, Desirée San Nicolás-Hernández, José E. Piñero, Jacob Lorenzo-Morales   +14 more
doaj   +1 more source

PPARα Agonist Suppresses Inflammation after Corneal Alkali Burn by Suppressing Proinflammatory Cytokines, MCP-1, and Nuclear Translocation of NF-κB

Molecules, 2018
We investigated the effect of a peroxisome proliferator-activated receptor α (PPARα) agonist after corneal alkali injury. Fenofibrate 0.05% (PPARα agonist group) or vehicle (Vehicle group) was topically instilled onto the rat cornea ...
Yuichiro Nakano, Masaaki Uchiyama, Takeshi Arima, Shinya Nagasaka, Tsutomu Igarashi, Akira Shimizu, Hiroshi Takahashi   +6 more
doaj   +1 more source

Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery [PDF]

, 2018
● AIM: To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.
Librando, Aloisa, Livani, Maria Luisa, Nebbioso, Marcella, Santamaria, Valentina, Sepe, Massimiliano   +4 more
core   +2 more sources

Classification of Human Retinal Microaneurysms Using Adaptive Optics Scanning Light Ophthalmoscope Fluorescein Angiography [PDF]

, 2014
Purpose. Microaneurysms (MAs) are considered a hallmark of retinal vascular disease, yet what little is known about them is mostly based upon histology, not clinical observation.
Carroll, Joseph, Chui, Toco Y.P., Cooper, Robert F., Dubow, Michael, Dubra, Alfredo, Gan, Alexander, Gentile, Ronald C., Hendrix, Vernon, Pinhas, Alexander, Rosen, Richard B., Shah, Nishit, Sulai, Yusufu N., Walsh, Joseph B., Weitz, Rishard   +13 more
core   +2 more sources

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz, Alio, Ambrosio, Djalilian, Dogru, Li, Nebbioso, Nebbioso, Patel, Rajan, Solomon, Suzuki, Toda, Wilson, Zhu   +14 more
core   +1 more source

Local variation in absolute water content of human and rabbit eye lenses measured by Raman microspectroscopy [PDF]

, 1989
Raman spectra were obtained from fresh, fixed and sliced rabbit lenses and from human lens slices. For all lenses and lens slices the ratio R, defined as the Raman intensity at 3390 cm−1 divided by the Raman intensity at 2935 cm−1, was measured at ...
Bot, Annet C.C., Greve, Jan, Huizinga, Alex, Mul, Frits F.M. de, Vrensen, Gijs F.J.M.   +4 more
core   +4 more sources

In vitro amoebicidal effects of arabinogalactan-based ophthalmic solution

International Journal for Parasitology: Drugs and Drug Resistance, 2021
The main corneal infections reported worldwide are caused by bacteria and viruses but, recently, the number of Acanthamoeba keratitis (AK) cases has increased.
M. Reyes-Batlle, I. Rodríguez-Talavera, I. Sifaoui, R.L. Rodríguez-Expósito, P. Rocha-Cabrera, J.E. Piñero, J. Lorenzo-Morales   +6 more
doaj   +1 more source

Bacteriologic and clinical efficacy of ofloxacin 0.3% versus ciprofloxacin 0.3% ophthalmic solutions in the treatment of patients with culture-positive bacterial keratitis.

, 2003
PURPOSE: To compare the efficacy and safety of ofloxacin 0.3% ophthalmic solution with ciprofloxacin 0.3% ophthalmic solution in patients with culture-positive bacterial keratitis.
George, C, Lu, KL, McDonnell, PJ, Prajna, NV, Selvaraj, S, Srinivasan, M   +5 more
core   +1 more source

The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options. [PDF]

, 2020
Homeostasis of the lacrimal functional unit is needed to ensure a well-regulated ocular immune response comprising innate and adaptive phases. When the ocular immune system is excessively stimulated and/or immunoregulatory mechanisms are disrupted, the ...
Lin, Meng C, Neri, Piergiorgio, Perez, Victor L, Periman, Laura M, Saban, Daniel R   +4 more
core   +1 more source