Results 1 to 10 of about 13,245 (221)
New England Journal of Medicine, 2010 Graves' orbitopathy is part of an autoimmune systemic disease which compiles hyperthyroidism, orbitopathy, dermopathy and acropachy. Stimulating antibodies against the TSH receptor play the central pathogenetic role. Main symptoms of Graves' orbitopathy comprise soft tissue inflammation, proptosis impairment of ocular motility and lid retraction ...
A, Eckstein, J, Esser
exaly +7 more sources
Teprotumumab for Thyroid-Associated Ophthalmopathy [PDF]
New England Journal of Medicine, 2017 BACKGROUND: Thyroid-associated ophthalmopathy, a condition commonly associated with Graves’ disease, remains inadequately treated. Current medical therapies, which primarily consist of glucocorticoids, have limited efficacy and present safety concerns ...
Terry J Smith +2 more
exaly +3 more sources
Cross-sectional study of thyroid associated orbitopathy in a South African thyroid clinic [PDF]
Journal of the Colleges of Medicine of South AfricaBackground: Thyroid-associated ophthalmopathy (TAO) is a common and debilitating manifestation of Graves’ disease (GD) associated with poor clinical outcomes including impaired quality-of-life (QoL) and socio-economic status.
Sandra De Vasconcelos +3 more
doaj +2 more sources
Thyroid-associated Ophthalmopathy
Türk Oftalmoloji Dergisi, 2017 Thyroid-associated ophthalmopathy is the most frequent extrathyroidal involvement of Graves’ disease but it sometimes occurs in euthyroid or hypothyroid patients.
Esra Şahlı, Kaan Gündüz
doaj +3 more sources
Predictors of Ophthalmic Manifestations in Patients with Ankylosing Spondylitis [PDF]
International Journal of Biomedicine, 2022 The aim of this study was to conduct a clinical and statistical analysis of ophthalmological manifestations in patients with Ankylosing Spondylitis (AS) using biologic disease-modifying antirheumatic drugs (bDMARDs) as a basic therapy.
Daria A. Karpova +5 more
doaj +1 more source
Insulin-Like Growth Factor Pathway and the Thyroid
Frontiers in Endocrinology, 2021 The insulin-like growth factor (IGF) pathway comprises two activating ligands (IGF-I and IGF-II), two cell-surface receptors (IGF-IR and IGF-IIR), six IGF binding proteins (IGFBP) and nine IGFBP related proteins.
Terry J. Smith
doaj +1 more source
Thyroid eye disease or Graves’ orbitopathy: What name to use, and why it matters
Frontiers in Endocrinology, 2022 There is currently no universally accepted name for inflammatory disease of the eye and orbit associated with thyroid autoimmune disease. Variability in terminology impedes the evaluation of scientific literature and clinical collaboration and can affect
Lilly H. Wagner +5 more
doaj +1 more source
Extraction (DSX) from Erigeron breviscapus modulates outward potassium currents in rat retinal ganglion cells [PDF]
International Journal of Ophthalmology, 2015 AIM: To investigate the effect of DSX, an active component extracted from Erigeron breviscapus, on the voltage-gated outward K+ channel currents in rat retinal ganglion cells (RGCs) by using electrophysiological method, and to explore the possible ...
Shuo Yin +4 more
doaj +1 more source
Taiwan Journal of Ophthalmology, 2023 Thyroid eye disease (TED) is characterized by progressive orbital inflammation. In severe cases, it can lead to dysthyroid optic neuropathy (DON), involving death of retinal ganglion cells and permanent vision loss.
Lillian Chien +3 more
doaj +1 more source
Application of Proteomics Analysis and Animal Models in Optic Nerve Injury Diseases
Brain Sciences, 2023 Optic nerve damage is a common cause of blindness. Optic nerve injury is often accompanied by fundus vascular disease, retinal ganglion cell apoptosis, and changes in retinal thickness.
Zhaoyang Meng +4 more
doaj +1 more source