Results 1 to 10 of about 14,434 (161)

Oral Embryonal Rhabdomyosarcom in an Adult Addict Man: a case report and review of literature [PDF]

Journal of Kerman University of Medical Sciences, 2021
Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, but rare in adults, especially those in the middle age and older.
Farzaneh Aghahosseini, Shahrzad Fooladvand, Nafiseh Sheykhbahaei   +2 more
doaj   +1 more source

Pronounced Declines in Meperidine in the US: Is the End Imminent?

Pharmacy, 2022
Background: Once a widely used analgesic in the United States (US), meperidine offered an alternative opioid to other opioids as a pain reliever and was widely assumed to be safer with acute pancreatitis.
Lavinia R. Harrison, Rhudjerry E. Arnet, Anthony S. Ramos, Poul A. Chinga, Trinidy R. Anthony, John M. Boyle, Kenneth L. McCall, Stephanie D. Nichols, Brian J. Piper   +8 more
doaj   +1 more source

Sociodemographic and clinical characteristics of patients with long-term remission with buprenorphine / naloxone in opiate use disorder

European Psychiatry, 2021
Introduction Buprenorphine/Naloxone (BP/NLX) is an effective drug combination used in long-term maintenance therapy in opiate use disorder (OUD). In some studies, abstinence over 180 days was defined as long-term remission (1).
Y. Kahya, A. Erdogan
doaj   +1 more source

An Examination of the Complex Pharmacological Properties of the Non-Selective Opioid Modulator Buprenorphine

Pharmaceuticals, 2023
The goal of this review is to provide a recent examination of the pharmacodynamics as well as pharmacokinetics, misuse potential, toxicology, and prenatal consequences of buprenorphine.
Leana J. Pande, Rhudjerry E. Arnet, Brian J. Piper   +2 more
doaj   +1 more source

Toward Composite Pain Biomarkers of Neuropathic Pain—Focus on Peripheral Neuropathic Pain

Frontiers in Pain Research, 2022
Chronic pain affects ~10–20% of the U.S. population with an estimated annual cost of $600 billion, the most significant economic cost of any disease to-date. Neuropathic pain is a type of chronic pain that is particularly difficult to manage and leads to
Monica M. Diaz, Jacob Caylor, Irina Strigo, Imanuel Lerman, Brook Henry, Eduardo Lopez, Mark S. Wallace, Ronald J. Ellis, Alan N. Simmons, John R. Keltner   +9 more
doaj   +1 more source

Enlarged cavum septum pellucidum as a neurodevelopmental marker in adolescent-onset opiate dependence. [PDF]

PLoS ONE, 2013
Adolescent-onset exposure to highly addictive substances such as opiates may induce far-reaching deleterious effects on later mental and physical health.
Jaeuk Hwang, Jieun E Kim, Marc J Kaufman, Perry F Renshaw, Sujung Yoon, Deborah A Yurgelun-Todd, Yera Choi, Chansoo Jun, In Kyoon Lyoo   +8 more
doaj   +1 more source

Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection

Frontiers in Immunology, 2022
The twin pandemics of opioid abuse and HIV infection can have devastating effects on physiological systems, including on the brain. Our previous work found that morphine increased the viral reservoir in the brains of treated SIV-infected macaques.
Howard S. Fox, Meng Niu, Brenda M. Morsey, Benjamin G. Lamberty, Katy Emanuel, Palsamy Periyasamy, Shannon Callen, Arpan Acharya, Gregory Kubik, James Eudy, Chittibabu Guda, Shetty Ravi Dyavar, Courtney V. Fletcher, Siddappa N. Byrareddy, Shilpa Buch   +14 more
doaj   +1 more source

Variation in adverse drug events of opioids in the United States

Frontiers in Pharmacology, 2023
Background: The United States (US) ranks high, nationally, in opioid consumption. The ongoing increase in the misuse and mortality amid the opioid epidemic has been contributing to its rising cost.
Edward Y. Liu, Kenneth L. McCall, Brian J. Piper, Brian J. Piper   +3 more
doaj   +1 more source

Cocrystal of Codeine and Cyclopentobarbital

Molbank, 2023
The two-component compound formed by codeine and cyclopentobarbital was produced using grinding techniques and through evaporation from alcoholic solutions.
Thomas Gelbrich, Jascha Schinke, Ulrich J. Griesser   +2 more
doaj   +1 more source

Declines and pronounced regional disparities in meperidine use in the United States

Pharmacology Research & Perspectives, 2021
There have been increasing concerns about adverse effects and drug interactions with meperidine. The goal of this study was to characterize meperidine use in the United States.
John M. Boyle, Kenneth L. McCall, Stephanie D. Nichols, Brian J. Piper   +3 more
doaj   +1 more source