Results 91 to 100 of about 93,906 (293)

Chronic Treatment with Opiate Agonists in Bulgaria - Assessing the Quality of Life Using SF 36 v. 2

open access: yesFolia Medica, 2016
Introduction: Drug addictions to psychoactive substances are disorders with a complex bio-psycho-social genesis, which are characterized with chronic relapses.
Petrov Sava V.   +3 more
doaj   +1 more source

Brief report: Ketamine‐assisted “bridge therapy” for opioid tapering in complex cases

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25‐year‐old woman with OUD, chronic pain, and major depressive disorder underwent an 8‐week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Results Methadone
Mariana C. de Oliveira   +11 more
wiley   +1 more source

A Longitudinal Assessment of Endometriosis Patients Prescribed Cannabis‐Based Medicinal Products: A Case Series From the UK Medical Cannabis Registry

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter   +16 more
wiley   +1 more source

Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*

open access: yesAnaesthesia, EarlyView.
Summary Introduction Major lower extremity amputations occurring secondary to vascular disease remain prevalent worldwide. Pain surrounding these procedures is complex, multifactorial and associated with poor functional and psychosocial outcomes. The evidence base informing pain management approaches in major lower extremity amputations remain largely ...
Thanapon Ekkunagul   +81 more
wiley   +1 more source

Polysomnographic Correlates for the Risk of Relapse in Detoxified Opiate-Misuse Patients

open access: yesNeuropsychiatric Disease and Treatment, 2020
Ahmed Rady,1 Jaidaa Mekky,2 Tarek Moulokheya,1 Ahmed Elsheshai3 1Department of Psychiatry, Alexandria University School of Medicine, Alexandria, Egypt; 2Department of Neurology, Alexandria University School of Medicine, Alexandria, Egypt; 3El Mamoura ...
Rady A   +3 more
doaj  

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

open access: yesAndrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret   +5 more
wiley   +1 more source

Novel insights into mechanisms of inhibition of colonic motility by loperamide

open access: yesFrontiers in Neuroscience
BackgroundIt is well known that opiates slow gastrointestinal (GI) transit, via suppression of enteric cholinergic neurotransmission throughout the GI tract, particularly the large intestine where constipation is commonly induced. It is not clear whether
Nabil Parkar   +11 more
doaj   +1 more source

Swiss Recommendations for the Perinatal Care of Extremely Low Gestational Age Neonates

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To revise the 2011 Swiss recommendations for the perinatal care of extremely low gestational age neonates (ELGANs). Methods Based on review of recent literature, experts from various medical specialties involved in the perinatal care of ELGANs made suggestions for revisions.
Thomas M. Berger   +20 more
wiley   +1 more source

Clinical trajectories and medication response in TBC1D24‐related epilepsies

open access: yesEpilepsia, EarlyView.
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon   +9 more
wiley   +1 more source

Scoping Review of Sexual and Gender Minority Health Research in Ireland

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To map existing sexual and gender minority (SGM) health research in Ireland, identify gaps in literature and outline priorities for future research and healthcare. SGM is an umbrella term that includes people who identify as lesbian, gay, bisexual, transgender, queer or intersex and is sometimes abbreviated as LGBTQI+.
John P. Gilmore   +7 more
wiley   +1 more source

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