Results 91 to 100 of about 93,906 (293)
Chronic Treatment with Opiate Agonists in Bulgaria - Assessing the Quality of Life Using SF 36 v. 2
Introduction: Drug addictions to psychoactive substances are disorders with a complex bio-psycho-social genesis, which are characterized with chronic relapses.
Petrov Sava V. +3 more
doaj +1 more source
Brief report: Ketamine‐assisted “bridge therapy” for opioid tapering in complex cases
Abstract Background Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25‐year‐old woman with OUD, chronic pain, and major depressive disorder underwent an 8‐week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Results Methadone
Mariana C. de Oliveira +11 more
wiley +1 more source
ABSTRACT Background Although there is growing evidence supporting the use of cannabis‐based medicinal products (CBMPs) for the management of chronic pain, there is a paucity of data on their effect on endometriosis‐associated chronic pain. Aims This study aimed to perform an analysis of pain‐specific and general health‐related quality of life (HRQoL ...
Sara Getter +16 more
wiley +1 more source
Summary Introduction Major lower extremity amputations occurring secondary to vascular disease remain prevalent worldwide. Pain surrounding these procedures is complex, multifactorial and associated with poor functional and psychosocial outcomes. The evidence base informing pain management approaches in major lower extremity amputations remain largely ...
Thanapon Ekkunagul +81 more
wiley +1 more source
Polysomnographic Correlates for the Risk of Relapse in Detoxified Opiate-Misuse Patients
Ahmed Rady,1 Jaidaa Mekky,2 Tarek Moulokheya,1 Ahmed Elsheshai3 1Department of Psychiatry, Alexandria University School of Medicine, Alexandria, Egypt; 2Department of Neurology, Alexandria University School of Medicine, Alexandria, Egypt; 3El Mamoura ...
Rady A +3 more
doaj
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Novel insights into mechanisms of inhibition of colonic motility by loperamide
BackgroundIt is well known that opiates slow gastrointestinal (GI) transit, via suppression of enteric cholinergic neurotransmission throughout the GI tract, particularly the large intestine where constipation is commonly induced. It is not clear whether
Nabil Parkar +11 more
doaj +1 more source
Swiss Recommendations for the Perinatal Care of Extremely Low Gestational Age Neonates
ABSTRACT Aim To revise the 2011 Swiss recommendations for the perinatal care of extremely low gestational age neonates (ELGANs). Methods Based on review of recent literature, experts from various medical specialties involved in the perinatal care of ELGANs made suggestions for revisions.
Thomas M. Berger +20 more
wiley +1 more source
Clinical trajectories and medication response in TBC1D24‐related epilepsies
Abstract Objective Biallelic variants in TBC1D24 represent a rare cause of epilepsy and neurodevelopmental disorders, including severe developmental and epileptic encephalopathies. Here, we present the first attempt to delineate the longitudinal disease histories and effectiveness of antiseizure medications (ASMs) in TBC1D24‐related disorders.
Ealing Mondragon +9 more
wiley +1 more source
Scoping Review of Sexual and Gender Minority Health Research in Ireland
ABSTRACT Aim To map existing sexual and gender minority (SGM) health research in Ireland, identify gaps in literature and outline priorities for future research and healthcare. SGM is an umbrella term that includes people who identify as lesbian, gay, bisexual, transgender, queer or intersex and is sometimes abbreviated as LGBTQI+.
John P. Gilmore +7 more
wiley +1 more source

