Results 121 to 130 of about 14,434 (161)
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2023
Opiates are both therapeutical and illicit drugs used by the population. Notwithstanding the introduction of new psychoactive substances (NPS), in particular of new derivatives of fentanyl, opiates and heroin in particular, represents one of the most diffused illicit drug and still accounts for most of the seizures worldwide.
Pascali, Jennifer P. and Fais, Paolo
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Opiates are both therapeutical and illicit drugs used by the population. Notwithstanding the introduction of new psychoactive substances (NPS), in particular of new derivatives of fentanyl, opiates and heroin in particular, represents one of the most diffused illicit drug and still accounts for most of the seizures worldwide.
Pascali, Jennifer P. and Fais, Paolo
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Annual Review of Pharmacology and Toxicology, 1978 The extract of the opium poppy is among the oldest materials used for medicinal purposes, and the study of the major alkaloid in this extract, morphine. is one of the oldest areas of biological research. Our lack of understanding on the molecular level of how morphine and its analogues produce their effects may be in large part related to the fact that
Eric J. Simon, Jacob M. Hiller
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Opiate treatment for opiate withdrawal in newborn infants
Cochrane Database of Systematic Reviews, 2002Neonatal abstinence syndrome (NAS) due to opiate withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss and seizures. Treatments used to ameliorate symptoms and reduce morbidity include opiates, sedatives and non-pharmacological treatments.To assess the effectiveness and safety
Heather E. Jeffery +2 more
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Opiate receptors and endogenous opiates: Panorama of opiate research
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 19821. In the last ten years basic research on the mechanism of action of opiates has led to the clearcut demonstration of the existence of opiate receptors--possibly several slightly different kinds--in the nervous system. 2. A number of endogenous ligands also called endorphins or enkephalins for these receptors have been discovered that proved to be ...
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Journal of Neuroimmunology, 1998
This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral infections in injection drug users with the outcome of ...
Phillip K. Peterson +3 more
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This review on the effects of opiate use on infectious diseases discusses the complete spectrum of infections in the opiate user, including those of the lung, the GI tract, the skin, the skeletal system, and the CNS. There is both increased prevalence and increased severity of bacterial and viral infections in injection drug users with the outcome of ...
Phillip K. Peterson +3 more
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Neuropharmacology, 2011
Opiates are among the most powerful analgesics and pain-relieving agents. However, they are potentially extremely addictive thereby limiting their medical use, making them exceedingly susceptible to abuse and adding to the global drug problem. It is believed that positive memories associated with the pleasurable effects of opiates and negative memories
Dacher, Matthieu, Nugent, Fereshteh S.
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Opiates are among the most powerful analgesics and pain-relieving agents. However, they are potentially extremely addictive thereby limiting their medical use, making them exceedingly susceptible to abuse and adding to the global drug problem. It is believed that positive memories associated with the pleasurable effects of opiates and negative memories
Dacher, Matthieu, Nugent, Fereshteh S.
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Autoanalgesia: Opiate and non-opiate mechanisms
Neuroscience & Biobehavioral Reviews, 1980Autoanalgesia (behaviorally-activated antinociception) was elicited by lesion-induced hyperemotionality or the classical conditioning of fear to the environmental stimuli associated with measuring antinociception. Both hyperemotionality and antinociception exhibited parallel decline in septal-lesioned rats with daily handling and in VMH-lesioned rats ...
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Journal of Comparative and Physiological Psychology, 1980
Beginning at 15 days of age. Long-Evans rat pups were trained to run toward their home cage in a T-maze task. Morphine (.5-1.0 mg/kg sc) slowed initial acquisition running times but did not change the number of trials required to learn the position habit. Morphine markedly impeded extinction of the homing behavior.
Jaak Panksepp, Fatma G. DeEskinazi
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Beginning at 15 days of age. Long-Evans rat pups were trained to run toward their home cage in a T-maze task. Morphine (.5-1.0 mg/kg sc) slowed initial acquisition running times but did not change the number of trials required to learn the position habit. Morphine markedly impeded extinction of the homing behavior.
Jaak Panksepp, Fatma G. DeEskinazi
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Trends in Pharmacological Sciences, 1992
Opiates interact with cell surface receptors on neurons involved in the transmission of information along neural pathways that are related to behaviours essential for the life of the self and of the species. Opiates are provided with powerful and multifaceted rewarding properties that are fundamental for the acquisition, maintenance and relapse of ...
DI CHIARA, GAETANO, NORTH RA
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Opiates interact with cell surface receptors on neurons involved in the transmission of information along neural pathways that are related to behaviours essential for the life of the self and of the species. Opiates are provided with powerful and multifaceted rewarding properties that are fundamental for the acquisition, maintenance and relapse of ...
DI CHIARA, GAETANO, NORTH RA
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Anaesthesia and Intensive Care, 1987
Current use of opioids in anaesthesia is reviewed with particular emphasis on the use of opioids in anaesthetic doses, techniques that recently have become popular in cardiovascular anaesthesia. A major benefit of opioid anaesthesia (particularly fentanyl) is the cardiovascular stability which obtains during induction and throughout operation, even in
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Current use of opioids in anaesthesia is reviewed with particular emphasis on the use of opioids in anaesthetic doses, techniques that recently have become popular in cardiovascular anaesthesia. A major benefit of opioid anaesthesia (particularly fentanyl) is the cardiovascular stability which obtains during induction and throughout operation, even in
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