Results 21 to 30 of about 14,434 (161)
Morphine and codeine, two of the most common opioids, are widely used in the clinic for different types of pain. Morphine is one of the most potent agonists for the μ-opioid receptor, leading to the strongest analgesic effect.
Mona Kamelan Zargar Zarin+3 more
doaj +1 more source
Investigating the Complications and Consequences of Myocardial Infarction between Abusers and Non-abusers of Opiate: A Cross-sectional Study in the South of Iran [PDF]
Background: One of the major risk factors in cardiovascular diseases is Opiate abuse. Accordingly, the present study aims to investigate the complications and consequences of myocardial infarction between Abusers and Non-abusers of Opiate in the south of
Mojtaba Farjam+5 more
doaj +1 more source
Optimizing post-operative opiate prescribing following gynecologic surgery
Background: Post-operative opiate prescribing has traditionally been stratified by procedure type with little regard for patient opiate utilization. We sought to evaluate peri-operative factors associated with patient opiate utilization post-operatively ...
Katherine M. Croft+5 more
doaj
Opioid overdose remains a problem in the United States despite pharmacotherapies, such as buprenorphine, in the treatment of opioid use disorder. This study characterized changes in buprenorphine use.
Zhi‐Shan Hsu+8 more
doaj +1 more source
Abuse of tropicamide eye drops: review of clinical data
Over the past 15 years, the increasing nonmedical use of tropicamide ophthalmic drops has been reported in Europe, coinciding with an increase in opioid addiction and drug-related mortality.
Val Bellman+6 more
doaj +1 more source
Binding Pathway of Opiates to $μ$ Opioid Receptors Revealed by Unsupervised Machine Learning [PDF]
Many important analgesics relieve pain by binding to the $\mu$-Opioid Receptor ($\mu$OR), which makes the $\mu$OR among the most clinically relevant proteins of the G Protein Coupled Receptor (GPCR) family. Despite previous studies on the activation pathways of the GPCRs, the mechanism of opiate binding and the selectivity of $\mu$OR are largely ...
arxiv +1 more source
Heroin addiction hijacks the Nucleus Accumbens: craving and reactivity to naturalistic stimuli [PDF]
Drug-related cues hijack attention away from alternative reinforcers in drug addiction, inducing craving and motivating drug-seeking. However, the neural correlates underlying this biased processing, its expression in the real-world, and its relationship to cue-induced craving are not fully established, especially in opioid addiction.
arxiv
For downloading the full-text of this article please click here. Background and Objective: Considering the fact that few domestic and international studies have examined the role of spirituality in mental health and tendency to addition, the present ...
Seyed Aghil Nasimi+3 more
doaj
The Opium for the Poor Is Opium. Medicare Providers in States with Low Income Prescribe High Levels of Opiates [PDF]
The majority of Medicare opioid prescriptions originate with family practice and internal medicine providers. I show that the average number of Medicare opium prescriptions by these providers vary strongly by state and that 54% of the variance is accounted for by the state median household income. I also show that there is a very similar relationship
arxiv +1 more source
Firsthand Opiates Abuse on Social Media: Monitoring Geospatial Patterns of Interest Through a Digital Cohort [PDF]
In the last decade drug overdose deaths reached staggering proportions in the US. Besides the raw yearly deaths count that is worrisome per se, an alarming picture comes from the steep acceleration of such rate that increased by 21% from 2015 to 2016.
arxiv +1 more source