Results 311 to 320 of about 152,289 (375)
Some of the next articles are maybe not open access.
Journal of Comparative and Physiological Psychology, 1980
Beginning at 15 days of age. Long-Evans rat pups were trained to run toward their home cage in a T-maze task. Morphine (.5-1.0 mg/kg sc) slowed initial acquisition running times but did not change the number of trials required to learn the position habit. Morphine markedly impeded extinction of the homing behavior.
Jaak Panksepp, Fatma G. DeEskinazi
openaire +3 more sources
Beginning at 15 days of age. Long-Evans rat pups were trained to run toward their home cage in a T-maze task. Morphine (.5-1.0 mg/kg sc) slowed initial acquisition running times but did not change the number of trials required to learn the position habit. Morphine markedly impeded extinction of the homing behavior.
Jaak Panksepp, Fatma G. DeEskinazi
openaire +3 more sources
Trends in Pharmacological Sciences, 1992
Opiates interact with cell surface receptors on neurons involved in the transmission of information along neural pathways that are related to behaviours essential for the life of the self and of the species. Opiates are provided with powerful and multifaceted rewarding properties that are fundamental for the acquisition, maintenance and relapse of ...
DI CHIARA, GAETANO, NORTH RA
openaire +4 more sources
Opiates interact with cell surface receptors on neurons involved in the transmission of information along neural pathways that are related to behaviours essential for the life of the self and of the species. Opiates are provided with powerful and multifaceted rewarding properties that are fundamental for the acquisition, maintenance and relapse of ...
DI CHIARA, GAETANO, NORTH RA
openaire +4 more sources
Anaesthesia and Intensive Care, 1987
Current use of opioids in anaesthesia is reviewed with particular emphasis on the use of opioids in anaesthetic doses, techniques that recently have become popular in cardiovascular anaesthesia. A major benefit of opioid anaesthesia (particularly fentanyl) is the cardiovascular stability which obtains during induction and throughout operation, even in
openaire +2 more sources
Current use of opioids in anaesthesia is reviewed with particular emphasis on the use of opioids in anaesthetic doses, techniques that recently have become popular in cardiovascular anaesthesia. A major benefit of opioid anaesthesia (particularly fentanyl) is the cardiovascular stability which obtains during induction and throughout operation, even in
openaire +2 more sources
Opiate Analgesia: Evidence for Mediation by a Subpopulation of Opiate Receptors
Science, 1980Naloxazone, a hydrazone derivative of the opiate antagonist naloxone, has a high affinity for opiate receptor binding sites. Naloxazone injections reduce opiate receptor binding to extensively washed mouse brain membranes for more than 24 hours, suggesting that the effect is irreversible.
Gavril W. Pasternak +2 more
openaire +3 more sources
The Role of Endorphins in Opiate Addiction, Opiate Withdrawal, and Recovery
Psychiatric Clinics of North America, 1983Substance abuse and addiction to various substances are enormous public health problems. Opiates are among the oldest drugs used and abused by humans. The authors trace the history of opiate use from Assyrian poppy art through modern times, and investigate the roles endorphins play in addiction, withdrawal, and recovery.
William S. Rea, Mark S. Gold
openaire +3 more sources
Opiate receptor binding—enhancement by opiate administration in vivo
Biochemical Pharmacology, 1976Abstract Administration of opiate agonists and antagonists to mice produces a dose-dependent 50–100 per cent enhancement of stereospecific [ 3 H]dihydromorphine or [ 3 H]naloxone binding to brain homogenates within 5 min. Three opiate antagonists are 10–1000 times more potent in eliciting this increase in binding than their structurally analogous ...
Candace B. Pert, Solomon H. Snyder
openaire +3 more sources
2004
The term “opioid” applies to any substance, whether endogenous or synthetic, that produces morphine-like effects. Opiates are restricted to synthetic morphine-like drugs with non-peptidic structure. Opium is an extract of the juice of the poppy Papaver somniferum, which has been used socially and medicinally as early as 400 to 300 bc.
Seyed Adel Moallem +3 more
openaire +2 more sources
The term “opioid” applies to any substance, whether endogenous or synthetic, that produces morphine-like effects. Opiates are restricted to synthetic morphine-like drugs with non-peptidic structure. Opium is an extract of the juice of the poppy Papaver somniferum, which has been used socially and medicinally as early as 400 to 300 bc.
Seyed Adel Moallem +3 more
openaire +2 more sources
Perioperative opiate requirements in children with previous opiate infusion
Pediatric Anesthesia, 2011SummaryBackground: Critically ill children often require continuous opiate infusions. Tolerance may develop requiring a weaning strategy to prevent withdrawal symptoms. These children may also require subsequent surgical procedures. This is the first study to investigate whether previously opiate‐tolerant patients require higher doses of opiates for ...
Laura D. Cassidy +4 more
openaire +2 more sources
Addiction, 1994
AbstractOpiate withdrawal is one of the longest studied and most well described withdrawal syndromes. Opiate withdrawal has been described as akin to a moderate to severe flu‐like illness. Opiate withdrawal is appropriately described as subjectively severe but objectively mild.
openaire +2 more sources
AbstractOpiate withdrawal is one of the longest studied and most well described withdrawal syndromes. Opiate withdrawal has been described as akin to a moderate to severe flu‐like illness. Opiate withdrawal is appropriately described as subjectively severe but objectively mild.
openaire +2 more sources
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Nature, 1975J. Hughes +5 more
semanticscholar +1 more source