Results 81 to 90 of about 152,289 (375)

Former heroin-dependent alcohol use disorder patients. prevalence, addiction history and clinical features [PDF]

, 2015
Aims: To examine the prevalence of former heroin dependence (FHA) in Alcohol Use Disorder (AUD) patients; to compare the clinical characteristics of FHA-AUD patients versus AUD patients without any past use of heroin at alcohol treatment entry; to ...
Ceccanti, Mauro, Maremmani, Angelo Giovanni Icro, Maremmani, Icro, Pacini, Matteo   +3 more
core   +1 more source

Cannabinoid Transmission in the Prelimbic Cortex Bidirectionally Controls Opiate Reward and Aversion Signaling through Dissociable Kappa Versus μ-Opiate Receptor Dependent Mechanisms

Journal of Neuroscience, 2013
Cannabinoid, dopamine (DA), and opiate receptor pathways play integrative roles in emotional learning, associative memory, and sensory perception. Modulation of cannabinoid CB1 receptor transmission within the medial prefrontal cortex (mPFC) regulates ...
Tasha Ahmad, Nicole M. Lauzon, X. de Jaeger, S. Laviolette   +3 more
semanticscholar   +1 more source

FIGO good practice recommendations on preconception care: A strategy to prevent preterm birth

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preterm birth (PTB) remains one of the leading causes of neonatal mortality and long‐term morbidity worldwide, with minimal progress being made in reducing its incidence, particularly in low‐resource settings. Preconception care is recognized as an effective strategy for PTB prevention; however, the fact that more than half of pregnancies ...
Leticia Irma Ojeda, Catalina M. Valencia, Natalia Cardozo Buitrago, Dilly Anumba, Wondimu Gudu, Ana Bianchi, Bo Jacobsson, on behalf of the FIGO Committee for Preterm Birth, Catalina M. Valencia González, Dilly Anumba, Wondimu Gudu, Bo Jacobsson, Nancy Sierra Lozada, Leticia Ojeda, Madhuri Patel, Andrew Shennan, Rodrigo Rigoni, Priya Soma‐Pillay, Sherri Ann Suplido, Ana Daneva, Sikolia Wanyonyi, Haim Abenhaim   +21 more
wiley   +1 more source

Opiate Exposure and Withdrawal Induces a Molecular Memory Switch in the Basolateral Amygdala between ERK1/2 and CaMKIIα-Dependent Signaling Substrates

Journal of Neuroscience, 2013
Opiate reward memories are powerful triggers for compulsive opiate-seeking behaviors. The basolateral amygdala (BLA) is an important structure for the processing of opiate-related associative memories and is functionally linked to the mesolimbic dopamine
D. Lyons, X. de Jaeger, L. Rosen, Tasha Ahmad, Nicole M. Lauzon, J. Zunder, L. Coolen, W. Rushlow, S. Laviolette   +8 more
semanticscholar   +1 more source

Dextromethorphan versus Dextrorphan: A Quantitative Comparison of Antitussive Potency following Separate Administration of Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract To assess the antitussive effects of dextrorphan (DOR) relative to its parent compound, dextromethorphan (DEX) a double‐blind, randomized, placebo‐controlled crossover study was conducted in 23 healthy volunteers using citric acid cough challenge test after administering placebo, DEX, or DOR.
Saeed Rezaee, Caroline E. Wright, Alyn H. Morice, Amin Rostami‐Hodjegan   +3 more
wiley   +1 more source

Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]

, 2013
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér, Kovács, Krisztina J., Milanes, Victoria M., Nunez, Cristina, Pintér-Kübler, Bernadett, Polyák, Ágnes, Zelei, Edina   +6 more
core   +2 more sources

Intranasal Naloxone During Recurrent Exercise in Individuals with Type‐1 Diabetes Mellitus: Evaluation of the Clinical Predictors of Pharmacokinetics and Exposure–Response

The Journal of Clinical Pharmacology, EarlyView.
Abstract Impaired awareness of hypoglycemia (IAH) impacts 25%–30% of individuals with type 1 diabetes mellitus (T1D), potentially leading to severe outcomes due to reduced symptom perception. Naloxone, a mu‐opioid receptor antagonist, shows promise as a preventive measure against IAH.
Omar N. Al Yacoub, Shen Cheng, Mohamed S. Fayed, James Fisher, Jillian Brooks, Elizabeth Seaquist, Anjali Kumar, Amir Moheet, Lynn Eberly, Lisa D. Coles   +9 more
wiley   +1 more source

Polysomnographic Correlates for the Risk of Relapse in Detoxified Opiate-Misuse Patients

Neuropsychiatric Disease and Treatment, 2020
Ahmed Rady,1 Jaidaa Mekky,2 Tarek Moulokheya,1 Ahmed Elsheshai3 1Department of Psychiatry, Alexandria University School of Medicine, Alexandria, Egypt; 2Department of Neurology, Alexandria University School of Medicine, Alexandria, Egypt; 3El Mamoura ...
Rady A, Mekky J, Moulokheya T, Elsheshai A   +3 more
doaj  

Addiction: Alcohol and Substance Abuse in Judaism

Religions, 2014
This article outlines a history of rulings and beliefs about addiction in Judaism, covering alcohol and substance use and addiction, in the context of a brief account of the development of the status of addiction.
Kate Miriam Loewenthal
doaj   +1 more source

Novel insights into mechanisms of inhibition of colonic motility by loperamide

Frontiers in Neuroscience
BackgroundIt is well known that opiates slow gastrointestinal (GI) transit, via suppression of enteric cholinergic neurotransmission throughout the GI tract, particularly the large intestine where constipation is commonly induced. It is not clear whether
Nabil Parkar, Nabil Parkar, Nabil Parkar, Nick J. Spencer, Luke Wiklendt, Trent Olson, Wayne Young, Wayne Young, Patrick Janssen, Warren C. McNabb, Julie E. Dalziel, Julie E. Dalziel   +11 more
doaj   +1 more source