Results 61 to 70 of about 16,312 (224)

Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients - Frequency and correlates of use [PDF]

, 2003
This retrospective study aims to determine whether there is a difference in the additional consumption of alcohol between addicts treated with methadone or dihydrocodeine (DHC) and untreated addicts injecting heroin.
Backmund, Markus, Eichenlaub, Dieter, Meyer, Kirsten, Schütz, Christian G., Soyka, Michael   +4 more
core   +1 more source

THE FATHERS, COMPUTERS AND US

Modern Theology, EarlyView.
Abstract This essay, designed as a complement to opinions expressed by Rowan Williams and some speakers at the conference in his honour, explores features of early Christianity which suggest a positive evaluation of artificial intelligence. Noting that the fear of reducing humans to machines has been joined in the modern age by the fear that machines ...
Mark J. Edwards
wiley   +1 more source

The Efficacy of Spirulina on Cognitive Function, Psychological and Clinical Indicators in Men Patients Under Methadone Therapy (a Randomized Trial)

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
In male patients receiving methadone maintenance therapy (MMT), Spirulina tablet (500 mg twice daily) for 12 weeks significantly reduced anxiety and stress score compared to the placebo group. However, no significant effects were observed for the depression, sexual function, craving, and cognitive performance measures between the two groups.
Morteza Zamani Asadolah‐poor‐kashi, Peyman Mamsharifi, Freshteh Haerifar, Mehrdad Simani, Amir Ghaderi, Fateme Mehrzad   +5 more
wiley   +1 more source

Changes in substance use during outpatient treatment for substance use disorders: a prospective Norwegian cohort study from 2016 to 2020

Substance Abuse Treatment, Prevention, and Policy, 2021
Background Continuous use of amphetamines, alcohol, benzodiazepines, cannabis, cocaine, or opioids contributes to health impairments, increased morbidity, and overdose deaths among patients with substance use disorders (SUDs).
Jørn Henrik Vold, Fatemeh Chalabianloo, Christer F. Aas, Else-Marie Løberg, Kjell Arne Johansson, Lars Thore Fadnes   +5 more
doaj   +1 more source

Efficacy and safety of a selective partial agonist for nociception/orphanin‐FQ peptide (NOP) receptors in patients with insomnia disorder

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 172-185, January 2026.
Aims Insomnia is a common sleep disorder, affecting up to 20% of the world population and adversely impacting productivity, health, and overall well‐being. Although pharmacologic options exist to treat insomnia, the health‐related quality of life for patients who are prescribed hypnotics is no higher than for those who are not, revealing a significant ...
Garth T. Whiteside, Ellie He, Manjunath S. Shet, Mingyan Zhou, Maha Ahmad, Stephen C. Harris   +5 more
wiley   +1 more source

The Efficacy of Pharmacological Treatment of Depression in Anorexia Nervosa and Underweight Patients: A Systematic Review

European Eating Disorders Review, Volume 34, Issue 1, Page 55-70, January 2026.
ABSTRACT Objective Major depressive disorder (MDD) is a frequent comorbidity in anorexia nervosa (AN). This review aimed to evaluate evidence on the effectiveness of pharmacological treatments for MDD in underweight individuals. Method A systematic review was conducted using PubMed, Medline, PsycINFO, and Web of Science through March 2025.
M. J. Besjes, S. H. W. Mares, A. A. van Elburg, J. Spijker   +3 more
wiley   +1 more source

Injecting equipment schemes for injecting drug users : qualitative evidence review [PDF]

, 2009
This review of the qualitative literature about needle and syringe programmes (NSPs) for injecting drug users (IDUs) complements the review of effectiveness and cost-effectiveness.
Akhionbare, Kate, Bagnall, Anne-Marie, Burrell, Kim, Cattan, Mima   +3 more
core  

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonist [PDF]

, 2013
Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles.
Birkás, Erika, Bozó, Beáta, Cinar, Resat, Dochnal, Roberta Beatrix, Fábián, Gabriella, Kicsi, Emese Gabriella, Kékesi, Orsolya, Murányi, Marianna, Mácsai, Mónika, Szabó, Gyula, Szűcs, Mária, Tóth, Géza, Zentai, András   +12 more
core   +3 more sources

Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Methadone is used in hospitalized children to treat pain and iatrogenic opiate withdrawal. Optimal pediatric dosing for both enteral and intravenous methadone is unknown. We conducted two prospective, multi‐center, open‐label studies to characterize the pharmacokinetics of methadone in the pediatric population.
Kevin M. Watt, Elizabeth J. Thompson, Lisa Lam, Kanecia Zimmerman, Christoph P. Hornik, Andrew M. Atz, Allison Fernandez, Susan R. Hupp, Varsha Bhatt‐Mehta, Daniel K. Benjamin Jr, Ravinder Anand, Michael Cohen‐Wolkowiez, Daniel Gonzalez, P. Brian Smith, Edmund V. Capparelli, the Best Pharmaceuticals for Children Act — Pediatric Trials Network Steering Committee   +15 more
wiley   +1 more source

Leveraging the role of community pharmacists in the prevention, surveillance, and treatment of opioid use disorders

Addiction Science & Clinical Practice, 2019
The global rise in opioid-related harms has impacted the United States severely. Current efforts to manage the opioid crisis have prompted a re-evaluation of many of the existing roles in the healthcare system, in order to maximize their individual ...
Paxton Bach, Daniel Hartung
doaj   +1 more source