Results 81 to 90 of about 15,739 (221)

Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates [PDF]

, 2016
Fentanyl is a powerful opiate analgesic typically used for the treatment of severe and chronic pain, but its prescription is strongly limited by the well-documented side-effects.
Benyhe, Sa ́ndor, CARRADORI, Simone, Csaba To ̈mbo ̈ly, Erdei, Anna I., Ferenc O. ̈tvos, Ferenc Za ́dor, Fidanza, Lorenzo, Marzoli, Francesca, Mirzaie, Sako, MOLLICA, Adriano, MONTI, LUDOVICA, Moriello, Aniello Schiano, Novellino, Ettore, Petrocellis, Luciano De, PIERETTI, stefano, Samavati, Reza, STEFANUCCI, AZZURRA, Szabolcs Dvora ́csko, Szucs, Edina   +18 more
core   +1 more source

Drug Policy and the HIV Pandemic in Russia and Ukraine [PDF]

, 2004
Over the past three years Russia and Ukraine have experienced one of the fastest growing HIV pandemics in Europe. In contrast to other parts of the world, the main driver behind the rate of infection is injecting drug use. Recent government policies have
Klein, Axel, Roberts, Marcus, Trace, Mike   +2 more
core  

Engaging Gut‐to‐Brain Signalling to Treat Alcohol Use Disorder

Addiction Biology, Volume 31, Issue 3, March 2026.
ABSTRACT According to the 2023 National Survey on Drug Use and Health (NSDUH), 28.9 million people ages 12 and older in the United States had alcohol use disorder (AUD) in the past year. Although chronic alcohol use contributes to numerous health disorders as well as being an economic burden, there are few medications approved for treatment of AUD, and
Paula L. Hoffman, Giordano de Guglielmo, Valentina Vengeliene, Wolfgang Kunze, Christina L. Lebonville, Jerome D. Swinny, Amanda J. Roberts, Olivier George, Karen‐Anne McVey Neufeld, Alexandra Dunbar, Laura M. Saba, Ruolin Ma, Leandro F. Vendruscolo, Howard C. Becker, Rainer Spanagel, Boris Tabakoff   +15 more
wiley   +1 more source

Mobile telephone contingency management to encourage adherence to supervised medication among individuals most at risk of non-adherence to opioid agonist treatment: a study protocol for a feasibility study (TIES2)

Pilot and Feasibility Studies
Background Supervision of opioid agonist treatment (OAT) ensures that individuals take their correct daily dose to minimise withdrawal and craving, safeguard against diversion and overdose, and receive optimal benefit from OAT. There is an urgent need to
Nicola Metrebian, Carol-Ann Getty, Ewan Carr, Timothy Weaver, Stephen Pilling, Mike Kelleher, Jenny Scott, John Strang   +7 more
doaj   +1 more source

Putting Families First: How the Opioid Epidemic is Affecting Children and Families, and the Child Welfare Policy Options to Address It [PDF]

, 2019
: Opioids and Child Welfare Across the country, placements in foster care are rising. In 2016, the U.S. Department of Health and Human Services reported that 273,539 children in the U.S. entered foster care.
American Academy of Pediatrics Council on Foster Care, Adoption, and Kinship Care, Greiner, Mary V, Laris, Zach, Waite, Douglas   +3 more
core   +1 more source

Difficulties associated with outpatient management of drug abusers by general practitioners. A cross-sectional survey of general practitioners with and without methadone patients in Switzerland [PDF]

, 2005
Background In Switzerland, general practitioners (GPs) manage most of the patients receiving methadone maintenance treatment (MMT). Methods Using a cross-sectional postal survey of GPs who treat MMT patients and GPs who do not, we studied the ...
Anne Pelet, Jacques Besson, Alain Pécoud, Bernard Favrat, A Byrne, M Weinrich, DA Fiellin, EA Salsitz, D Lewis, J Keen, M Gossop, A Glanz, A Davies, k Barrau, JR Cooper, SN Miller, J Strang, T Blaney, C Matherson, EC Strain, S Simoens, F Faggiano, B McAvoy   +22 more
core   +1 more source

Dentate Gyrus Engrams in Fear and Reward: Mechanistic Principles, Critical Gaps, and Paths to Translation

Journal of Neurochemistry, Volume 170, Issue 3, March 2026.
Memories of rewarding experiences powerfully shape behavior, yet when maladaptive, they can drive psychiatric conditions including addiction, depression, and PTSD. Memory traces, or engrams, have been extensively studied for fear memories in the hippocampal dentate gyrus.
Lorianna M. Colón, Oluwatoni A. Famuyide, Amelia J. Eisch   +2 more
wiley   +1 more source

HCV epidemiology in high-risk groups and the risk of reinfection [PDF]

, 2016
Injecting risk behaviours among people who inject drugs (PWID) and high-risk sexual practices among men who have sex with men (MSM) are important routes of hepatitis C virus (HCV) transmission.
Dalgard, Olav, Lo Re III, Vincent, Macias, Juan, Midgard, Havard, Palmateer, Norah, Pineda, Juan A., Weir, Amanda   +6 more
core   +2 more sources

Predominant Symptom in Gastroparesis: Relationships to Quality of Life, Treatments, and Outcome

Neurogastroenterology &Motility, Volume 38, Issue 3, March 2026.
In patients with gastroparesis, the most common predominant symptoms were nausea, vomiting, and abdominal pain. Impaired QOL varied with patients' predominant symptom, with abdominal pain associated with poorer QOL. Over 48 weeks, GSCI improved ≥ 1 in a minority of patients, more often in patients with predominant symptoms of nausea and bloating, less ...
Henry P. Parkman, Laura A. Wilson, William L. Hasler, Madhusudan Grover, Bruno P. Chumpitazi, Helen Burton‐Murray, Irene Sarosiek, Baha Moshiree, Geoffrey A. Preidis, Robert J. Shulman, Laura A. Miriel, Dave Shade, Braden Kuo, Richard W. McCallum, Thomas L. Abell, Pankaj J. Pasricha, for the NIDDK Gastroparesis Clinical Research Consortium   +16 more
wiley   +1 more source

The newer opioid agonist treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older harm reduction treatment [PDF]

, 2016
Background: Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatment (OAT) in high-threshold ...
Bacciardi, Silvia, Bizzarri, Jacopo V., Casetti, Valentina, Conca, Andreas, Giovanni Icro Maremmani, Angelo, Maremmani, Icro, Piacentino, Daria, Rovai, Luca, Sanna, Livia   +8 more
core   +1 more source