Results 81 to 90 of about 133,922 (249)

Navigating the Hepatic Immune Landscape With Fine Needle Aspiration of the Liver—An Emerging Technique

Liver International, Volume 45, Issue 11, November 2025.
ABSTRACT Background and Aims Hepatic immune cell analysis is critical for understanding chronic inflammatory liver diseases, such as primary sclerosing cholangitis (PSC) and steatotic liver disease. However, liver immunoprofiling is limited due to reliance on end‐stage disease liver explants.
Kate Diana Lynch, Fabiola Curion, Hing‐Yuen Yeung, Charlotte Rich‐Griffin, Devika Agarwal, Helen Ferry, Andrew Slater, Emma Louise Culver, Roger William Chapman, Satish Keshav, Paul Klenerman, Calliope Athena Dendrou   +11 more
wiley   +1 more source

TRPC6 effects on albumin permeation, nephrin shedding, and apoptosis in podocytes: Role of calcineurin and metalloproteases

Physiological Reports, Volume 13, Issue 21, November 2025.
Certain ligands of pattern recognition receptors can induce a rapid increase in albumin permeability across a podocyte monolayer that can be seen in 1 h, but activation of TRPC6 for up to 24 h does not mimick this process. However, continuous TRPC6 activation for 24 h results in nephrin ectodomain shedding that calcineurin activation and ...
Eun Young Kim, Stuart E. Dryer
wiley   +1 more source

Genetics of Response to ECT, TMS, Ketamine and Esketamine

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 7, Page 88-102, October 2025.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin, Murat Altinay, Kala Bailey, Mahendra T. Bhati, Brent R. Carr, Susan K. Conroy, Khurshid Khurshid, William M. McDonald, Brian J. Mickey, James W. Murrough, Sean M. Nestor, Thomas Nickl‐Jockschat, Irving M. Reti, Gerard Sanacora, Nicholas T. Trapp, Biju Viswanath, Jesse H. Wright, Peter P. Zandi, James B. Potash   +18 more
wiley   +1 more source

Leveraging the role of community pharmacists in the prevention, surveillance, and treatment of opioid use disorders

Addiction Science & Clinical Practice, 2019
The global rise in opioid-related harms has impacted the United States severely. Current efforts to manage the opioid crisis have prompted a re-evaluation of many of the existing roles in the healthcare system, in order to maximize their individual ...
Paxton Bach, Daniel Hartung
doaj   +1 more source

Injecting equipment schemes for injecting drug users : qualitative evidence review [PDF]

, 2009
This review of the qualitative literature about needle and syringe programmes (NSPs) for injecting drug users (IDUs) complements the review of effectiveness and cost-effectiveness.
Akhionbare, Kate, Bagnall, Anne-Marie, Burrell, Kim, Cattan, Mima   +3 more
core  

A Systematic Review of Substance Misuse Treatment Processes and Outcomes as Implemented in Prisons for Men in the UK

Criminal Behaviour and Mental Health, Volume 35, Issue 5, Page 270-289, October 2025.
ABSTRACT Background With a rising prison population, a substantial portion of whom are identified as substance misusers, it is important to understand the availability of treatment pathways, their successes and areas for improvement. Given the likely importance of national factors in criminal justice and substance use service provision, we chose to ...
Kim Barnett, Noor Butt, Rosie Allen, Pauline Goodlad, Anne Krayer, Adam O'Neill, Peter Huxley, Catherine Robinson, Emily Peckham, Rob Poole   +9 more
wiley   +1 more source

Peer involvement and cross-sector efforts in establishing integrated treatment of hepatitis C virus infection for people with substance use disorders: experiences from Norway

Substance Abuse Treatment, Prevention, and Policy, 2019
Background For people with opioid dependence in Norway, chronic hepatitis C virus (HCV) infections contribute to high mortality and high morbidity. Around 50% of patients in medically assisted rehabilitation (MAR) have been shown to have HCV, and the ...
Ole Jørgen Lygren, Ronny Bjørnestad, Else-Marie Løberg, Martine Lepsøy Bonnier, Vibeke Bråthen Buljovcic, Kjell Arne Johansson, Lars T. Fadnes, for the INTRO-HCV Study Group   +7 more
doaj   +1 more source

Outlining the role of experiential expertise in professional work in health care service co-production

International Journal of Qualitative Studies on Health & Well-Being, 2021
Patient and public involvement is widely thought to be important in the improvement of health care delivery and in health equity.Purpose: The article examines the role of experiential knowledge in service co-production in order to develop opiate ...
Hannele Palukka, Arja Haapakorpi, Petra Auvinen, Jaana Parviainen   +3 more
doaj   +1 more source

Effects of Drug Administration on Postoperative Pain in Orthognathic Surgery: A Systematic Review

Clinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objectives This systematic review aims to offer indications on how drug administration affects postoperative pain in patients undergoing orthognathic surgery. Material and Methods We searched Pubmed, Scopus, and Web of Science for articles pertaining to our research topic.
Gianna Dipalma, Angelo Michele Inchingolo, Lilla Riccaldo, Roberta Morolla, Pietro Lauria, Roberto Vito Giorgio, Valeria Colonna, Benito F. P. Pennacchio, Antonio Mancini, Andrea Palermo, Alessio Danilo Inchingolo, Francesco Inchingolo   +11 more
wiley   +1 more source

A baseline audit of opiate substitution therapy and 12-week retention in treatment

European Psychiatry, 2007
Background:The National Treatment Agency has set 12-week retention as an outcome measure for the treatment of opiate addiction. Both methadone and buprenorphine show research evidence of efficacy in this condition. To ensure that these medications are being used optimally, we performed a baseline audit in two drug treatment services in North East ...
A. Akioye, R. Cohen
openaire   +2 more sources