Results 91 to 100 of about 10,078,256 (288)

Pharmacoepidemiology of Oxycodone in the USA: An Observational Study of ARCOS, Medicaid, and Medicare Drug Databases

open access: yesPharmacology Research & Perspectives
The US continues to battle an opioid crisis, substantially influenced by prescription opioids, with nearly 80 000 opioid‐related deaths in 2023. This study aims to characterize oxycodone's distribution in the United States (US) from 2000 to 2023 using ...
Jay P. Solgama   +3 more
doaj   +1 more source

Perceived Opioid-Related Health Beliefs Among Homeless-Experienced Individuals Engaging in Opioid Use Disorder Treatment

open access: yesSubstance Use & Misuse
People experiencing homelessness are disproportionately affected by opioid use disorder (OUD), yet treatment engagement remains low. Understanding opioid-related health beliefs in this population may inform more tailored interventions. To characterize opioid-related health beliefs among homeless-experienced individuals with OUD and examine their ...
Danielle R. Fine   +4 more
openaire   +2 more sources

Fiscal Year 2022

open access: yes, 2020
This report describes the activities and highlights accomplishments of the Texas Council on Alzheimer’s Disease and Related Disorders Council during fiscal years 2019 and 2020 and also provides recommendations for the following fiscal ...
Texas Council on Alzheimer's Disease & Related Disorders
core  

Exploring new avenues: Psychedelic‐assisted therapy for young people

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou   +3 more
wiley   +1 more source

The Effects of Maternal Opium Abuse on Fetal Heart Rate using Non-Stress Test

open access: yesIranian Journal of Medical Sciences, 2016
Background: Opium is one of the most commonly abused opiates in developing countries including Iran. Considering the importance of maternal health on the newborn, we aimed to assess the effect of opium abuse on fetal heart rate (FHR) characteristics in a
Fatemeh Keikha   +2 more
doaj  

Opioid-related diagnoses and HIV, HCV and mental disorders: using Pennsylvania hospitalisation data to assess community-level relationships over space and time

open access: yesJournal of Epidemiology and Community Health, 2019
Background We assessed the community-level spatiotemporal connexions between hospitalisations for common opioid comorbidities (HIV, hepatitis C (HCV) and mental disorders) and opioid-related hospitalisations in the current and previous year. Methods
Natalie Sumetsky   +2 more
openaire   +3 more sources

The influence of discouragement, anxiety and anger on pain: an examination of the role of endogenous opioids [PDF]

open access: yes, 2005
Animal research suggests that exposure to inescapable stressors can lead to an endogenous opioid-mediated form of pain inhibition, known as stress-induced analgesia (SIA).
Frew, Ashley Kim
core  

Development of a nalmefene formulation suitable for a community‐use auto‐injector

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano   +6 more
wiley   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili   +6 more
wiley   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen   +4 more
wiley   +1 more source

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