Results 111 to 120 of about 205,220 (260)

Levels of brain related proteins in cerebrospinal fluid: An aid in the differential diagnosis of parkinsonian disorders

open access: yes, 2009
Parkinsonian disorders such as Parkinson's disease (PD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal degeneration (CBD), are a large group of common neurodegenerative diseases.
Zetterberg, Henrik,   +3 more
core   +1 more source

From Opioid Pain Management to Opioid Crisis in the USA: How Can Public-Private Partnerships Help?

open access: yesFrontiers in Medicine, 2019
The current opioid crisis in the USA arose from (at first) successful opioid pain management in three waves, starting in the'90s. Today, USA patients consume opioid drugs on a massive scale.
Larissa Bolliger, Hilde Stevens
doaj   +1 more source

The Role of Opioids on Motor Activity in Physio-pathological Conditions

open access: yes, 2009
To date, four principal classes of opioid peptide receptors, μ (MOP), κ (KOP), δ (DOP) and ORL- 1 (NOP) have been identified and cloned. The experimental and clinical importance of this receptor family has been amply demonstrated in many diseases ...
Mabrouk, Omar Sharif
core  

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Is There Less Opioid Abuse in States Where Marijuana Has Been Decriminalized, Either for Medicinal or Recreational Use? A Clin-IQ

open access: yesJournal of Patient-Centered Research and Reviews, 2019
Opioid use, abuse, and associated mortality have reached an epidemic level. In some states, cannabis is being used to treat chronic pain. To examine the hypothesis that medical marijuana legislation may reduce adverse opioid-related outcomes if patients ...
Aaron M. Wendelboe   +6 more
doaj   +1 more source

The role of concomitant drugs in the aetiology of fatal heroin- and methadone- related overdose [PDF]

open access: yes, 2008
Heroin and methadone poisoning are significant causes of death of young people in the United Kingdom. In a high proportion of these fatalities concomitant substances are also detected.
Oliver, Phillip
core  

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng   +9 more
wiley   +1 more source

Perioperative opioid related disorders on outcomes following lower extremity fracture fixation: Comparative analysis from a multicenter national database

open access: yesInjury
Opioid use can be common in patients who require surgical fixation of lower extremity fractures. While common, these medications place patients at risk for developing opioid-related disorders (OD) which can in turn affect bony healing and propagate endocrinopathies.
Daniel E. Pereira   +4 more
openaire   +2 more sources

Things We Do for No Reason™: Withholding opioids among patients with acute pain and opioid use disorder

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Hospitalists care for patients with acute pain who have an opioid use disorder and require pain management. Hospitalists may withhold opioids for acute pain due to a variety of reasons. However, adequate pain management in patients with opioid use disorder, including with opioids, is the standard of care. This piece explains how to best manage
Anna‐Maria South   +2 more
wiley   +1 more source

The influence of discouragement, anxiety and anger on pain: an examination of the role of endogenous opioids

open access: yes, 2005
Animal research suggests that exposure to inescapable stressors can lead to an endogenous opioid-mediated form of pain inhibition, known as stress-induced analgesia (SIA).
Frew, Ashley Kim
core  

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