Results 131 to 140 of about 205,220 (260)

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

What smartphone apps exist to support recovery from opioid use disorder? A content analysis of publicly available opioid-related smartphone apps

Addiction Science & Clinical Practice
Abstract Background An estimated 84,181 people died due to opioid overdose in 2022 alone [1]. Mobile technologies may offer an additional pathway to provide support to people seeking recovery from opioid use disorder (OUD). To this end, we conducted a content analysis of opioid-related apps to determine to what extent
Alivia Williamson, Behnam Heydarshahi, Diadora Finley-Abboud, Lili Massac, Lindsay Jacobson, Naicha Christophe, Judeline Joseph, Allison Futter, Susanne S. Hoeppner, Bettina B. Hoeppner   +9 more
openaire   +3 more sources

Challenges of Pain in Parkinson's Disease: Results from the OCEAN Study

Movement Disorders, EarlyView.
Abstract Background Pain is a common non‐motor symptom in Parkinson’s disease (PD) and is often associated to fluctuations. Objective The OpiCapone Effect on motor fluctuations and pAiN (OCEAN) study evaluated the effect of opicapone on fluctuation‐related pain when added to levodopa therapy in PD patients.
Kallol Ray Chaudhuri, Joaquim J. Ferreira, Angelo Antonini, Olivier Rascol, Monica M. Kurtis, Alexander Storch, José‐Francisco Rocha, Raquel Costa, Diogo Magalhães, Guillermo Castilla‐Fernández, Helena C. Brigas, Joerg Holenz, Per Odin, on behalf of the OCEAN study group   +13 more
wiley   +1 more source

Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder

Genetic Epidemiology
ABSTRACT Persistent opioid use after surgery is a common morbidity outcome associated with subsequent opioid use disorder, overdose, and death. While phenotypic associations have been described, genetic associations remain unidentified.
Aubrey C. Annis, Vidhya Gunaseelan, Albert V. Smith, Gonçalo R. Abecasis, Daniel B. Larach, Matthew Zawistowski, Stephan G. Frangakis, Chad M. Brummett   +7 more
openaire   +2 more sources

Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

Obesity, EarlyView.
ABSTRACT Objective This study aimed to evaluate the association of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) with risks of osteoporosis, major osteoporotic fractures, and degenerative musculoskeletal disorders in nondiabetic adults with obesity compared with other obesity medications.
Jie‐Syuan Wu, Lee‐Yuan Lin, Jia‐Wei Sun, Wei‐Ting Yu, Fara Silvia Yuliani, Shyh‐Hsiang Lin   +5 more
wiley   +1 more source

Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedures. Study Design Retrospective cohort study. Setting TriNetX US Collaborative Research Network. Methods The
Michael Liu, Austin Lee, Salim Hayek, Shawn Li   +3 more
wiley   +1 more source

A Renal Impairment Subgroup Analysis of the Safety and Efficacy of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Non-Cancer Pain Receiving Opioid Therapy

Journal of Pain Research, 2020
Lynn R Webster,1 Martin E Hale,2 Tadaaki Yamada,3 James E Wild4 1PRA Health Sciences, Salt Lake City, UT, USA; 2Gold Coast Research LLC, Plantation, FL, USA; 3Shionogi, Inc., Florham Park, NJ, USA; 4Upstate Clinical Research Associates, Williamsville, NY,
Webster LR, Hale ME, Yamada T, Wild JE
doaj  

Mental Health Risk Factors for Postoperative Pain in Head and Neck Free Flap Reconstruction Patients

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Head and neck cancer (HNC) surgery is associated with postoperative pain and comorbid mental health disorders (MHDs). This study assessed predictors of postoperative pain and inpatient pain service consultation following free flap reconstruction (FFR). Study Design Retrospective cohort. Setting Single‐institution database.
Daniel R. S. Habib, Sindhura Sridhar, Heezy Suh, Daniel Larson, Brooke B. Swain, Kelly Vittetoe, Donald Sengstack, Michael C. Topf, Melanie D. Hicks   +8 more
wiley   +1 more source

Cognitive behaviour therapy as an evidence-based intervention for opioid use disorder: a systematic review

Journal of the Pakistan Medical Association
Objective: To explore the effectiveness of cognitive behaviour therapy as an evidence-based intervention for patients with opioid use disorder and to estimate the effect of cognitive behaviour therapy in mental health care settings.
Mafia Shahzadi, Khalid Mahmood Bhati
doaj   +1 more source

Impact of Institutional Protocol on Urinary Catheter Outcome Measures in Orthopedic Children Treated With Epidural Analgesia

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Epidural analgesia is commonly used for pain control after major lower‐limb orthopedic surgery in children, but it is associated with a risk of postoperative urinary retention. Consequently, urinary catheters are often placed and left in situ for the full duration of epidural analgesia, despite the potential risks of prolonged ...
Idan Katz, Tomer Talmy, Dor Barami, Tal S. Beckmann, Barry Danino, Yotam Lior, Margaret Ekstein   +6 more
wiley   +1 more source