Results 131 to 140 of about 289,251 (304)

Parkinsonism & Related Disorders [PDF]

, 2013
Texto completo. Acesso restrito. p. 279–281Swallowing impairment is the main cause of pulmonary infection and death in Parkinson's disease (PD). To date, there is no established effective treatment to restore swallowing function among these subjects ...
Monteiro, Larissa, Melo, Ailton
core   +2 more sources

Pilot trial of THRIVE: A peer‐delivered sexual and intimate partner violence prevention program for women in substance use treatment

Journal of Traumatic Stress, EarlyView.
Abstract High rates of interpersonal violence exposure and trauma‐related mental health concerns among women in substance use treatment underscore the need for violence prevention services in these settings. Peer support specialists can play a crucial role in increasing access to trauma‐focused services and overcoming barriers, such as stigma and ...
Heidi M. Zinzow, Lauren Smalls, Irene Pericot‐Valverde, Meghan Shank, Madelyn Brancato, Greyson Chapman, Allison Smith, Caroline Greco, Kacey Eichelberger, Kimbley Smith, Alain H. Litwin   +10 more
wiley   +1 more source

Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?. [PDF]

Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
core  

Nail Surgery in Children: Specific Challenges and Practical Considerations

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail surgery in children represents a specific field within dermatologic surgery. Although the procedures themselves are largely similar to those performed in adults, the indications, technical constraints, and perioperative management differ substantially. Pediatric nail disorders are often clinically recognizable, which frequently limits the
F. Lamoline, B. Richert
wiley   +1 more source

Naloxone antagonizes the local antihyperalgesic effect of fentanyl in burnt skin of healthy humans [PDF]

, 2007
The aim of this study was to investigate local opioid effects in the inflamed skin of healthy human volunteers. To induce inflammation, the circular tip of a 10-mm-diameter probe was heated to 48°C and applied for 120 seconds to a site on each forearm of
Hammond, G.R., Drummond, P.D., Robertson, L.   +2 more
core   +1 more source

Plasma and Synovial Fluid VEGF‐A and Neuropilin‐1 in Knee Osteoarthritis: Associations With Radiographic Severity, Pain Sensitization‐Related Features, and Disease Burden

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to investigate associations of plasma and synovial fluid vascular endothelial growth factor A (VEGF‐A) and neuropilin‐1 (NRP1) levels with radiographic severity, pain sensitization‐related features, and disease burden in knee osteoarthritis (KOA). Plasma VEGF‐A and NRP1 were measured by sandwich ELISA in 120 patients with KOA (
Cheng‐Ju Tan
wiley   +1 more source

What smartphone apps exist to support recovery from opioid use disorder? A content analysis of publicly available opioid-related smartphone apps

Addiction Science & Clinical Practice
Abstract Background An estimated 84,181 people died due to opioid overdose in 2022 alone [1]. Mobile technologies may offer an additional pathway to provide support to people seeking recovery from opioid use disorder (OUD). To this end, we conducted a content analysis of opioid-related apps to determine to what extent
Alivia Williamson, Behnam Heydarshahi, Diadora Finley-Abboud, Lili Massac, Lindsay Jacobson, Naicha Christophe, Judeline Joseph, Allison Futter, Susanne S. Hoeppner, Bettina B. Hoeppner   +9 more
openaire   +3 more sources

Postoperative Effects of Celecoxib on Opioid Use and Pain Control After Benign Oropharyngeal Surgery

The Laryngoscope, EarlyView.
This study evaluated how the addition of celecoxib to a multimodal pain regimen following tonsillectomy + adenoidectomy, or uvulopalatopharyngoplasty (UPPP) + tonsillectomy affects postoperative opioid use and pain control. Patients who received celecoxib consumed significantly fewer opioids compared to the historic control group, with similar ...
Alana Platukus, Praneet Kaki, Anastasia Kaffenes, Udeerna Tippabhatla, Jared Robinson, Jaehee Kim, Erin Creighton, Meghan Crippen, Maurits Boon, Colin Huntley   +9 more
wiley   +1 more source

A Renal Impairment Subgroup Analysis of the Safety and Efficacy of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Non-Cancer Pain Receiving Opioid Therapy

Journal of Pain Research, 2020
Lynn R Webster,1 Martin E Hale,2 Tadaaki Yamada,3 James E Wild4 1PRA Health Sciences, Salt Lake City, UT, USA; 2Gold Coast Research LLC, Plantation, FL, USA; 3Shionogi, Inc., Florham Park, NJ, USA; 4Upstate Clinical Research Associates, Williamsville, NY,
Webster LR, Hale ME, Yamada T, Wild JE
doaj  

Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder

Genetic Epidemiology
ABSTRACT Persistent opioid use after surgery is a common morbidity outcome associated with subsequent opioid use disorder, overdose, and death. While phenotypic associations have been described, genetic associations remain unidentified.
Aubrey C. Annis, Vidhya Gunaseelan, Albert V. Smith, Gonçalo R. Abecasis, Daniel B. Larach, Matthew Zawistowski, Stephan G. Frangakis, Chad M. Brummett   +7 more
openaire   +2 more sources