Results 151 to 160 of about 205,220 (260)

Eating disorders in weight-related therapy (EDIT) : protocol for a systematic review with individual participant data meta-analysis of eating disorder risk in behavioural weight management

open access: yes, 2023
: The Eating Disorders In weight-related Therapy (EDIT) Collaboration brings together data from randomised controlled trials of behavioural weight management interventions to identify individual participant risk factors and intervention strategies that ...
Mensinger, Janell L.   +66 more
core  

Core stability in women with and without chronic pelvic pain

open access: yesPM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin   +5 more
wiley   +1 more source

Oral methylnaltrexone does not negatively impact analgesia in patients with opioid-induced constipation and chronic noncancer pain

open access: yesJournal of Pain Research, 2018
Lynn R Webster,1 Robert J Israel2 1PRA Health Sciences, Salt Lake City, UT, USA; 2Clinical and Medical Affairs, Salix Pharmaceuticals, Bridgewater, NJ, USA Purpose: An oral formulation of methylnaltrexone has been developed for treating opioid-induced ...
Webster LR, Israel RJ
doaj  

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Parkinsonism & Related Disorders

open access: yes, 2013
Texto completo. Acesso restrito. p. 279–281Swallowing impairment is the main cause of pulmonary infection and death in Parkinson's disease (PD). To date, there is no established effective treatment to restore swallowing function among these subjects ...
Monteiro, Larissa, Melo, Ailton
core   +1 more source

An Age‐Friendly Approach to Caring for Chronic Lung Disease in the Ambulatory Setting

open access: yesRespirology, EarlyView.
ABSTRACT Many common chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD), have much greater prevalence among older adults and as a result, pose a substantial burden of morbidity, disability, and mortality. The care of older adults with chronic lung disease necessitates an age‐friendly approach
Angela O. Suen   +3 more
wiley   +1 more source

Exploring the role of mu opioid receptor (OPRM1) and CYP2B6 gene variations for methadone pharmacogenomics. Can these variations be used to advance toxicological interpretation post-mortem?.

open access: yes
Methadone is increasingly involved in drug overdose cases and the molecular actions of the drug in vivo are largely unknown requiring elucidation. This study set out to examine the relationship between methadone toxicity and CYP2B6 and mu (μ) opioid ...
Bunten, Hannah
core  

Addressing the unique challenges of opioid use disorder in women [PDF]

open access: yes
Tuesday, January 17, 2017 at 1 p.m. ESTDeaths from drug overdoses are the number one cause of injury death in the U.S. Most of these deaths are related to the misuse of prescription opioids and heroin.

core  

Innovative Microneedle Patches for Psoriasis Treatment: A Dual Approach With Methotrexate‐Zinc and Difelikefalin for Enhanced Therapeutic Outcomes

open access: yesSmall, EarlyView.
This study presents a novel dual‐layer microneedle platform for psoriasis treatment, integrating rapid itch relief with sustained immunomodulatory and antibacterial effects. By combining difelikefalin and methotrexate‐zinc, this system effectively targets pruritus, epidermal hyperplasia, immune dysregulation, and infection, offering a promising ...
Xiaolong Xu   +5 more
wiley   +1 more source

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