Results 141 to 150 of about 205,220 (260)
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Austin VonAxelson +9 more
wiley +1 more source
Codeine and Metabolite Concentrations in the Breastfed Neonate
ABSTRACT Analgesic effect from codeine is from its metabolite, morphine. Morphine is formed by the O‐demethylation of codeine and that enzyme is controlled by the cytochrome P450 2D6. More than 60 alleles in the CYP2D6 gene have been identified. This spectrum of polymorphism can be categorized into four groups: poor (PM), intermediate (IM), normal (NM),
Brian J. Anderson, Jacqueline A. Hannam
wiley +1 more source
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles +3 more
wiley +1 more source
Worldwide, an opioid epidemic continues to escalate. While the scientific community has recognized substance use disorders as a biophysiological disease, society continues to view addiction as a social problem and not a medical one.
Bonfim, Julia +3 more
core +1 more source
Efeitos comportamentais e bioquímicos do ácido ascórbico em modelos de depressão e mania [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Bioquímica, Florianópolis, 2015.Os transtornos de humor estão associados a altos índices de morbidade, mortalidade e custo ...
Ribeiro, Camille Mertins
core
Purpose: This study aimed to determine the median effective volume (EV50) of 0.2% ropivacaine for ultrasound‐guided axillary brachial plexus block (ABPB) in children aged 6–10 years, using the Dixon up‐and‐down method. The EV50 was 0.350 mL/kg (95% CI: 0.197–0.362 mL/kg), calculated by isotonic regression and bootstrapping.
Tauseef Ahmad +11 more
wiley +1 more source
Multimodal Treatment of Neck Pain in Multiple System Atrophy
Movement Disorders Clinical Practice, EarlyView.
Bianca Caliò +2 more
wiley +1 more source
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager +3 more
wiley +1 more source
Background/Objectives: Recent studies have identified some concerns related to the occurrence of eye disorders in offspring of opioid-prescribed mothers, and especially so in those exposed to methadone.
Stefania Chiappini +7 more
doaj +1 more source
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source

