Results 171 to 180 of about 289,251 (304)

Targeting Opioid-Related Deaths: Prevalence, Perspectives and the Potential Role of Oxytocin in Opioid Use Disorder [PDF]

open access: yes
Opioid-related deaths are at record levels in the UK and contribute to over half of all drug-related deaths. Opioid use is complex and involves biological, psychological and socioeconomic influences which can trigger craving for opioids.
Houghton, B.
openaire   +3 more sources

Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea

open access: yesRespirology, EarlyView.
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara   +1 more
wiley   +1 more source

Firearms as a Market‐Driven Epidemic: Potential Pathways to Reduce Preventable Firearm‐Related Harm in the United States

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points For half a century, firearm‐related deaths and injuries have been endemic in the United States, with COVID‐19 contributing to a record high of 48,830 deaths in 2021, an epidemic rate increase. By 2023, national trends masked a significant 10‐fold difference in firearm‐related death rates among states.
ESZTER RIMÁNYI   +8 more
wiley   +1 more source

Impacts of Global Cannabis Policy Changes on Substance Use: A Systematic Review of Quasi‐Experimental Studies

open access: yesThe Milbank Quarterly, EarlyView.
Policy Points The liberalization of medical and recreational cannabis policies may increase cannabis initiation across age groups, with increased prevalence of cannabis use among young adults and adults and weaker effects among youth. Evidence also suggests increases in cannabis‐related health care utilization among adults.
SARAH B. WINDLE   +8 more
wiley   +1 more source

Differences in Risk Factors for Severe Preeclampsia and HELLP Syndrome in Singleton Versus Twin Pregnancies: A Population‐Based Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine whether the associations between pre‐pregnancy risk factors and severe preeclampsia/eclampsia (SPE) and/or HELLP syndrome differ between singleton and twin pregnancies. Design A population‐based retrospective cohort study. Setting British Columbia (BC), Canada.
Mackenzie Campbell   +17 more
wiley   +1 more source

Toronto's drug policy paradox: Harm reduction sites and drug police occurrences in Toronto neighborhoods (1992–2020)

open access: yesCriminology, EarlyView.
Abstract Discourse around drug policy presents a stark contrast between policing and harm reduction models, sparking debates on the state's regulatory versus protective role. Canada is an ideal case to study drug policy models due to its global recognition as a leader in harm reduction alongside continued reliance on policing of drugs.
Taylor Domingos
wiley   +1 more source

From Conflicting Outcomes to Mutual Losses: How Punitive Responses to Problematic Substance Use Suppress Help‐Seeking and Cause Harm

open access: yesHuman Resource Management Journal, EarlyView.
ABSTRACT Problematic substance use (PSU) is a significant, inadequately managed people management challenge. Drawing on the conflicting outcomes and mutual losses perspectives on HRM and employee wellbeing, and using Job Demands‐Resources theory to explain underlying strain‐driven loss cycles, we examine factors shaping PSU and help‐seeking among 575 ...
Karen Maher   +4 more
wiley   +1 more source

Benzodiazepine Use and Mortality Risk: A Nationwide Cohort Study on New Benzodiazepine Users With a 5‐Year Follow‐Up

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction We aimed to investigate the risks of all‐cause and cause‐specific mortality associated with dose‐dependent benzodiazepine and Z‐drug (BZDR) use in the Finnish population initiating new BZDR use with five‐year follow‐up. Methods Study subjects were included if BZDR use had started in 2006 with no BZDR dispensing during the ...
Hanna Särkilä   +7 more
wiley   +1 more source

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