Results 81 to 90 of about 10,513,249 (295)
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen +4 more
wiley +1 more source
Background Hepatitis C infection (HCV) and opioid use disorder (OUD) are syndemic in the U.S., thus primary care providers (PCPs) who treat OUD by prescribing buprenorphine can play key roles to advance HCV elimination targets.
Jocelyn R. James +7 more
doaj +1 more source
Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)-VK4-116, as a Non-Opioid Medication for the Treatment of Opioid Use Disorder. [PDF]
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Wu CK +15 more
europepmc +2 more sources
Update on the clinical use of buprenorphine: in opioid-related disorders.
To review the current evidence on buprenorphine-naloxone for the treatment of opioid-related disorders, with a focus on primary care settings.MEDLINE and the Cochrane Database of Systematic Reviews were searched. Evidence is mainly level I.Buprenorphine is a partial μ-opioid agonist and κ-opioid antagonist with a long half-life and less abuse potential
Simon, Ducharme +2 more
openaire +1 more source
Opioid medication treatment access is a public health priority aimed to improve opioid use treatment outcomes. However, Medicaid does not cover all forms of MOUD, particularly methadone, in many states. We examined associations between medication for opioid use disorder (MOUD) plans and substance use treatment discharge reason (e.g., completed ...
Melanie S, Askari +2 more
openaire +3 more sources
Paediatric clonidine medication errors: Findings from a multicentre French study
Aims This study aimed to describe the characteristics of medication errors involving clonidine in paediatric patients and reported to French Network of Pharmacovigilance and Poison Control Centres. Methods This retrospective observational study analysed clonidine‐related medication errors reported between 1985 and June 2024 in patients under 12 years ...
Eve‐Marie Thillard +8 more
wiley +1 more source
Safety of opioid patch initiation in Australian residential aged care [PDF]
Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Lisa Pont +5 more
core +1 more source
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
Comparison of early maladaptive schemas and parenting origins in patients with opioid abuse and non-abusers. [PDF]
Objective: The aim of this study was to examine the difference of early maladaptive schemas and parenting origins in opioid abusers and non-opioid abusers.
Mohammad Reza Jalali +3 more
doaj +1 more source
The US continues to battle an opioid crisis, substantially influenced by prescription opioids, with nearly 80 000 opioid‐related deaths in 2023. This study aims to characterize oxycodone's distribution in the United States (US) from 2000 to 2023 using ...
Jay P. Solgama +3 more
doaj +1 more source

