Results 61 to 70 of about 205,220 (260)

Assessing the effectiveness of problem-solving courts on the reduction of overdose deaths in the United States: A difference-in-difference study

Drug and Alcohol Dependence Reports, 2022
Background: Criminal justice-involved populations are disproportionately more likely to have an active substance use disorder (SUD) and experience a fatal overdose.
Zoe Lindenfeld, Sooyoung Kim, Ji Eun Chang   +2 more
doaj   +1 more source

National opioid pharmacotherapy statistics annual data collection 2012 [PDF]

, 2013
On a snapshot day in 2012, almost 47,000 clients received pharmacotherapy treatment for their opioid dependence at 2,226 dosing points around Australia, this report finds.SummaryAlmost 47,000 Australians received pharmacotherapy treatment for their ...

core  

Opioid-related emergency department visits and hospitalizations among patients with chronic gastrointestinal symptoms and disorders dually enrolled in the Department of Veterans Affairs and Medicare Part D

American Journal of Health-System Pharmacy, 2021
Abstract Purpose We examined the prevalence of, and factors associated with, serious opioid-related adverse drug events (ORADEs) that led to an emergency department (ED) visit or hospitalization among patients with chronic gastrointestinal (GI) symptoms and disorders dually enrolled in the Department ...
Salva N, Balbale, Lishan, Cao, Itishree, Trivedi, Jonah J, Stulberg, Katie J, Suda, Walid F, Gellad, Charlesnika T, Evans, Neil, Jordan, Laurie A, Keefer, Bruce L, Lambert   +9 more
openaire   +2 more sources

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source

Discharge locations after hospitalizations involving opioid use disorder among medicare beneficiaries

Addiction Science & Clinical Practice, 2022
Background Hospitalizations involving opioid use disorder (OUD) have been increasing among Medicare beneficiaries of all ages. With rising OUD-related acute care use comes the need to understand where post-acute care is provided and the capacities for ...
Patience Moyo, Melissa Eliot, Asghar Shah, Kimberly Goodyear, Eric Jutkowitz, Kali Thomas, Andrew R. Zullo   +6 more
doaj   +1 more source

Prescription Drug Monitoring Programs and Prescription Opioid-Related Outcomes in the United States. [PDF]

, 2023
Prescription drug monitoring programs (PDMPs) are a crucial component of federal and state governments' response to the opioid epidemic. Evidence about the effectiveness of PDMPs in reducing prescription opioid-related adverse outcomes is mixed.
Puac-Polanco, Victor, Li, Guohua, Chihuri, Stanford, Keyes, Katherine M, Fink, David S, Cerdá, Magdalena   +5 more
core   +1 more source

Correction: Computational phenotypes for patients with opioid-related disorders presenting to the emergency department

PLOS One
[This corrects the article DOI: 10.1371/journal.pone.0291572.].
R Andrew Taylor, Aidan Gilson, Wade Schulz, Kevin Lopez, Patrick Young, Sameer Pandya, Andreas Coppi, David Chartash, David Fiellin, Gail D'Onofrio   +9 more
openaire   +2 more sources

A community‐driven approach to address substance use and create a Great Plains American Indian addiction and recovery research agenda

American Journal of Community Psychology, EarlyView.
Abstract Substance use, specifically opioid and methamphetamine use, is of increasing concern among American Indian (AI) populations in the Great Plains. This community‐driven participatory study investigated the impacts of substance use and community‐defined needs in treating addiction.
Brynn Luger, Anna Kihlström, Brinda Sivaramakrishnan, Allison Kelliher, Frankie Kropp, Carmen Rosa, T. John Winhusen, Donald Warne, the CTN0129 participating Tribal communities   +8 more
wiley   +1 more source

Comparing cognitive behavioral therapy and social prescribing in patients with loneliness on long-term opioid therapy to reduce opioid misuse: protocol for a randomized controlled trial

Addiction Science & Clinical Practice
Background Patients with chronic pain on opioids frequently experience loneliness, which is associated with poorer health outcomes and higher risk for opioid misuse and opioid use disorder. Given that almost half of opioids are prescribed in primary care,
Sebastian T. Tong, Kris Pui Kwan Ma, Ajla Pleho, Brennan Keiser, Chialing Hsu, Dawn M. Ehde, Mary C. Curran, Judith I. Tsui, Patrick J. Raue, Kari A. Stephens   +9 more
doaj   +1 more source