Results 41 to 50 of about 10,513,249 (295)

Effective Chronic Pain Management and Responsible Opioid Prescribing: Aligning a Resident Workshop to a Protocol for Improved Outcomes

MedEdPORTAL, 2018
Introduction Effective chronic pain management is a core competency of internal medicine. Opioid use in the United States, both therapeutic and nonmedical in origin, has dramatically increased, as has the number of deaths due to opioid overdose.
Theresa E. Vettese, Neelima Thati, Renato Roxas   +2 more
doaj   +1 more source

Acute Poisoning in Elderly; a Five-Year Study (2008-2013) in Hamadan, Iran [PDF]

Asia Pacific Journal of Medical Toxicology, 2015
Background: A good proportion of poisoned patients treated at poisoning wards are elderly. This study was designed to evaluate the epidemiologic pattern of acute poisoning in elderly in Hamadan, western Iran.
Saeed Afzali, Mohammad Ali Seifrabiei, Seyed Kazem Taheri, Jahangir Pourabdollah   +3 more
doaj   +1 more source

Comparative Effects of Intensive Short-Term Dynamic Psychotherapy and Narcotics Anonymous Participation on Craving Among Men with Opioid Use Disorders

International Journal of Body, Mind and Culture
Objective: This study compared the effectiveness of Intensive Short-Term Dynamic Psychotherapy and Narcotics Anonymous participation in reducing craving among men with opioid use disorders. Methods and Materials: This quasi-experimental study used
Bita Bavadi, Malek Mirhashemi, Mina Mojtabaei   +2 more
doaj   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Acute opioid overdose in pediatric patients

Journal of the American College of Emergency Physicians Open
Recent increases in pediatric and adolescent opioid fatalities mandate an urgent need for early consideration of possible opioid exposure and specific diagnostic and management strategies and interventions tailored to these unique populations.
Stephen Sandelich, Gwen Hooley, George Hsu, Emily Rose, Tim Ruttan, Evan S. Schwarz, Erin Simon, Carmen Sulton, Jessica Wall, Ann M Dietrich   +9 more
doaj   +1 more source

Kappa Opioid Regulation of Stress-Related Behavior [PDF]

, 2010
Anxiety disorders affect roughly 40 million American adults in a given year. Those suffering from anxiety disorders often experience additional stress-linked illnesses, such as depression.
Harshberger, Erin
core  

Substance-Related Disorders

, 2017
This chapter reviews topics on substance-related disorders including alcohol-related disorders, stimulant-related disorders, caffeine-related disorders, cannabis-related disorders, stimulant-related disorders, hallucinogen-related disorders, tobacco ...
Shirshendu Sinha
core   +1 more source

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Subtypes of nonmedical opioid users: results from the national epidemiologic survey on alcohol and related conditions.

, 2020
To identify subtypes of nonmedical opioid users, gender variations in psychiatric disorders, and quality of life in a representative sample of adults.Analyses of data from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions (N ...
Wu, Li-Tzy, Blazer, Dan G, Woody, George E, Yang, Chongming   +3 more
core   +1 more source