Results 251 to 260 of about 648,698 (363)

Global burden of disease due to opioid, amphetamine, cocaine, and cannabis use disorders, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. [PDF]

PLoS One
Zhu DT, Kwon YIC, Lai A, Park AM, Barnes AJ, Chapman DA.   +5 more
europepmc   +1 more source

Cluster‐Randomized Trials in Emergency Care Research

Academic Emergency Medicine, EarlyView.
ABSTRACT Objective Cluster‐randomized trials (also called group‐randomized trials) are increasingly common in emergency care research. In such trials, groups of participants are allocated to different interventions based on naturally occurring “clusters,” such as clinics, hospitals, or emergency medical services agencies. In this methodological review,
Howard S. Kim, Jacob M. Schauer, Jody D. Ciolino   +2 more
wiley   +1 more source

Effect of varenicline on major adverse liver outcomes in alcohol‐associated liver disease: An exploratory analysis

Alcohol, Clinical and Experimental Research, EarlyView.
This real‐world study assessed whether varenicline improves outcomes in patients with ALD and AUD. Using data from a large electronic health record network, 1278 matched patients were analyzed. Varenicline use was associated with reduced all‐cause mortality and hepatic encephalopathy compared with FDA‐approved AUD therapies (acamprosate or naltrexone),
Pojsakorn Danpanichkul, Yanfang Pang, Donghee Kim, Thanathip Suenghataiphorn, Donghyun Ko, Andrew F. Ibrahim, Vitchapong Prasitsumrit, Kwanjit Duangsonk, Mazen Noureddin, Karn Wijarnpreecha, Suthat Liangpunsakul   +10 more
wiley   +1 more source

Gas station heroin- tianeptine and its impact: a systematic review and exploratory analysis. [PDF]

BMC Public Health
Parnia S, Jain L, Ali M, Sarfraz Z, Nasir MJ, Shah D, Fnu A, Atiq N, Shaikh PR, Ahmed R, Hower M, Karlapati S, Moazzam MT, Bazin B, Ahmed S.   +14 more
europepmc   +1 more source

Liver molecular networks associated with drinking behavior in nonhuman primates

Alcohol, Clinical and Experimental Research, EarlyView.
We identified hepatic molecular networks that differed between light drinkers (LD) and very heavy drinkers (VHD) before they were exposed to alcohol, as well as epigenetic differences between LD and VHD in response to the same amount of alcohol.
Laura A. Cox, James B. Daunais, Timothy D. Howard, Ge Li, Sobha Puppala, Jeannie Chan, Zeeshan Hamid, Samer Gawrieh, Sun Mi Lee, Betsy Ferguson, Kathleen A. Grant, Michael Olivier   +11 more
wiley   +1 more source

Research agenda evaluating measurement-based care for opioid use disorder among patients with co-occurring depressive disorders. [PDF]

Front Psychiatry
Ghitza UE.
europepmc   +1 more source

Exploring the role of gender on treatment outcomes in older adults with alcohol use disorder

Alcohol, Clinical and Experimental Research, EarlyView.
This study found that older adults (60+ years) with alcohol use disorder (AUD) experienced substantial and sustained improvements in drinking outcomes 1 year after treatment. While women started with lower alcohol consumption, they showed smaller reductions over time compared to men, resulting in similar levels at follow‐up.
Jeppe Sig Juelsgaard Tryggedsson, Kjeld Andersen, Silke Behrendt, Michael P. Bogenschutz, Gerhard Buehringer, Anette Søgaard Nielsen   +5 more
wiley   +1 more source

Predicted functional alterations in colonic microbiota metabolism underlie ethanol consumption and preference behavior in mice

Alcohol, Clinical and Experimental Research, EarlyView.
Using a free‐choice ethanol model, we show that mice switched from a high‐sugar/butter diet to AIN93G standard diet consume and prefer more alcohol than mice maintained on AIN93G. 16S profiling and inferred metabolome revealed reduced amino acid metabolism, increased secondary bile acid pathways, and lower microbiota‐derived SCFAs and selected amino ...
Mírian Velten Mendes, Thiago Cavalcante Lima, Mariana Siqueira Amormino, Jamil Silvano de Oliveira, Fernanda Lima Alvarenga Barroso, Gaëlle Boudry, Renato Elias Moreira‐Júnior, Ana Lúcia Brunialti‐Godard   +7 more
wiley   +1 more source

Women With Gynecologic Cancers: Screening for Substance Use Disorders Is Key. [PDF]

J Adv Pract Oncol
Shor L, Trotter K.
europepmc   +1 more source

Association of chronic opioid therapy and opioid use disorder with COVID-19-related hospitalization and mortality: Evidence from three health systems in the United States

Anh P. Nguyen, Ingrid A. Binswanger, Komal J. Narwaney, Morgan A. Ford, David L. McClure, Deborah Rinehart, Jason Lyons, Jason M. Glanz   +7 more
openalex   +1 more source