Safe Supply at Insite, North America's First Supervised Consumption Site: A Case Report of Reduced Harms From the Toxic Drug Supply in a Client Prescribed Powdered Fentanyl Alternative. [PDF]
Fairbairn N +4 more
europepmc +1 more source
The real-world safety evaluation of the selective NaV1.8 inhibitor suzetrigine: disproportionality analysis and flexible empirical bayes signals from FAERS with external triangulation. [PDF]
Lai K +6 more
europepmc +1 more source
Abstract Background and aims Cannabis cue reactivity paradigms are instrumental in studying the behavioral and neurocognitive mechanisms of cannabis use and cannabis use disorders; however, image sets used for cannabis cue reactivity paradigms vary between studies, and the lack of reliability and validity assessment hinders the quality of evidence they
Janna Cousijn +6 more
wiley +1 more source
Examining the relationship between opioid use and symptom-defined obstructive sleep apnea and sleep duration: A cross-sectional study. [PDF]
Li C +5 more
europepmc +1 more source
Beyond abstinence: Redefining success in cannabis use disorder treatment
Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin +3 more
wiley +1 more source
Comparative risk of psychiatric comorbidities associated with codeine and tramadol in patients with hip osteoarthritis: a nationwide population-based cohort study. [PDF]
Kim Y, Choo E, Shin S, Choi YJ.
europepmc +1 more source
Abstract Aims To investigate whether the treatment effect of extended‐release buprenorphine (BUP‐XR) on opioid‐free days in opioid use disorder (OUD) is mediated by reductions in opioid craving and improvements in personal functioning. Design and setting Exploratory causal mediation analysis using VanderWeele's four‐way decomposition framework in a 24 ...
John Marsden +11 more
wiley +1 more source
Why are Massachusetts opioid prescribing rates higher in rural versus urban areas? [PDF]
Modestino AS +4 more
europepmc +1 more source
Interindividual variability in the prevalence of OPRM1 and CYP2B6 gene variations may identify drug-susceptible populations [PDF]
Liang, Wei-Jun +3 more
core

