Results 101 to 110 of about 659,970 (390)

Behavioral architecture of opioid reward and aversion in C57BL/6 substrains

Frontiers in Behavioral Neuroscience, 2015
Drug liking versus drug disliking is a subjective motivational measure in humans that assesses the addiction liability of drugs. Variation in this trait is hypothesized to influence vulnerability versus resilience toward substance abuse disorders and ...
Stacey L Kirkpatrick, Camron D Bryant
doaj   +1 more source

Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]

, 2018
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J., Schwenk, Eric S., Viscusi, Eugene R.   +2 more
core   +1 more source

Chronic opioid pretreatment potentiates the sensitization of fear learning by trauma. [PDF]

, 2020
Despite the large comorbidity between PTSD and opioid use disorders, as well as the common treatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to subsequently modify PTSD-related behavior has not been well ...
Evans, Christopher J, Fanselow, Michael S, Li, Kevin, Pennington, Zachary T, Rajbhandari, Abha K, Trott, Jeremy M, Walwyn, Wendy M   +6 more
core   +1 more source

Neurobehavioral consequences of chronic intrauterine opioid exposure in infants and preschool children: a systematic review and meta-analysis [PDF]

, 2014
<b>Background</b><p></p> It is assumed within the accumulated literature that children born of pregnant opioid dependent mothers have impaired neurobehavioral function as a consequence of chronic intrauterine opioid use.<p>&
A Baldacchino, A Liberati, A Ornoy, A Sameroff, A Verdejo-Garcia, AJ Dunlop, Alex Baldacchino, American Psychiatric Association, B Hanson, BJ Cleary, Britannica, C Konijnenberg, C Konijnenberg, Colin McCowan, DE Hutchings, Dennis J Petrie, Department of Health (England) and the devolved administrations, DF Stroup, E Rotheram-Fuller, E Strauss, EK Emory, FM Wolf, GJ Demakis, H Cooper, HC Steinhausen, HE Jones, HE Jones, I Fihrer, I van Beusekom, IM Bernstein, J Cohen, J Cohen, J Keegan, J Kimber, J Prosser, JE Hunter, JN Whitham, JP Higgins, K Spiteri Cornish, Kathleen Arbuckle, KB Walhovd, KD Ersche, KK Zakzanis, L Manchikanti, L McGlone, LV Hedges, LV Hedges, LW Anderson, M Borenstein, M Borenstein, M Connock, M Farrell, M Grattan, M Pirastu, MD Lezak, MM de Cubas, National Collaborating Centre for Methods and Tools, NICE, NICHD, PS Bauman, R Bunikowski, R Cornish, R Hamilton, R King, RE Johnson, RG Orwin, RJ Sternberg, RW Hunt, S Darke, S Minozzi, S Salo, S Simeons, S Soepatmi, S Tong, Scottish Government, SL Grace, SL Hans, SL Hans, SM Petterson, SM Quinhana, SR Kandall, TB Huedo-Medina, TJ Ornstein, TS Rosen, V Moe, WH Organization, WK Lombardo   +86 more
core   +11 more sources

Association of Opioid Prescribing With Opioid Consumption After Surgery in Michigan

JAMA Surgery, 2019
Importance There is growing evidence that opioids are overprescribed following surgery. Improving prescribing requires understanding factors associated with opioid consumption.
Ryan Howard, Brian T Fry, V. Gunaseelan, J. Lee, J. Waljee, C. Brummett, D. Campbell, Elizabeth Seese, M. Englesbe, Joceline V. Vu   +9 more
semanticscholar   +1 more source

When Epidemics Collide: Coronavirus Disease 2019 (COVID-19) and the Opioid Crisis

Annals of Internal Medicine, 2020
COVID-19 could cause infection in persons with opioid use disorder, increase opioid overdose rates, reverse system-level gains in expanding access to medication for opioid use disorder, halt critical research, and prevent exacting legal reparations ...
W. Becker, D. Fiellin
semanticscholar   +1 more source

Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis‐Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis

Advanced Science, EarlyView.
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He, Bin Wu, Liuhu Han, Mingde Li, Wenli Guo, Jiajing Fu, Bin Mei, Eric R. Gross, Xuesheng Liu, Yao Lu   +9 more
wiley   +1 more source

CASTNet: Community-Attentive Spatio-Temporal Networks for Opioid Overdose Forecasting

, 2019
Opioid overdose is a growing public health crisis in the United States. This crisis, recognized as "opioid epidemic," has widespread societal consequences including the degradation of health, and the increase in crime rates and family problems.
A Kennedy-Hendricks, A Kolodny, AM Ertugrul, DS Burke, H Jalal, M Pierce, M Warner, NB King, PJ Gruenewald, R Hammersley, RA Rudd, S Hochreiter, S Scardapane, T Bennett, T Seddon   +14 more
core   +1 more source

Spatial Concentration of Opioid Overdose Deaths in Indianapolis: An Application of the Law of Crime Concentration at Place to a Public Health Epidemic [PDF]

, 2019
The law of crime concentration at place has become a criminological axiom and the foundation for one of the strongest evidence-based policing strategies to date.
Carter, Jeremy G., Mohler, George, Ray, Bradley   +2 more
core   +1 more source

Opioids and Operations [PDF]

Pediatrics, 2018
* Abbreviation: POU — : persistent opioid use The opioid crisis is currently front-page news.1 The United States leads the world in per capita opioid use as global consumption steadily increases.2,3 The percentage of deaths from opioids, fentanyl, and heroin is rising year after year.3 Harbaugh et al4 used a commercial claims database ...
openaire   +3 more sources