Results 141 to 150 of about 640,835 (387)

Hepatitis C Education and Screening in a Rural Northern Vermont MAT Clinic [PDF]

, 2020
Increases in hepatitis C infection rates have mirrored increases in opioid use disorder. This project attempted to determine screening rates of HCV in a medication assisted treatment clinic for opioid use disorder.
Fitzsimons, Jack
core   +1 more source

The use of international classification of diseases codes to identify hospital admissions linked with adverse drug events: Validation study

British Journal of Clinical Pharmacology, EarlyView.
Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová, Fatma Karapinar‐Çarkit, Daniala L. Weir   +2 more
wiley   +1 more source

Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor

eLife, 2018
The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Kathryn E Livingston, Jacob P Mahoney, Aashish Manglik, Roger K Sunahara, John R Traynor   +4 more
doaj   +1 more source

A Prospective Evaluation of Opioid Utilization After Upper-Extremity Surgical Procedures: Identifying Consumption Patterns and Determining Prescribing Guidelines. [PDF]

, 2016
BACKGROUND: Although adequate management of postoperative pain with oral analgesics is an important aspect of surgical procedures, inadvertent overprescribing can lead to excess availability of opioids in the community for potential diversion.
Abboudi, Jack, Ilyas, Asif M, Jones, Christopher M., Kim, Nayoung, Kirkpatrick, William, Leinberry, Charles, Liss, Frederic, Lutsky, Kevin F F., Maltenfort, Mitchell, Matzon, Jonas L., Wang, Mark L.   +10 more
core   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Patterns of drug treatment in patients with osteoarthritis and chronic low back pain in Japan: a retrospective database study

Journal of Pain Research, 2019
Manabu Akazawa,1 Wataru Mimura,1 Kanae Togo,2 Nozomi Ebata,3 Noriko Harada,4 Haruka Murano,5 Lucy Abraham,6 Koichi Fujii31Public Health and Epidemiology, Meiji Pharmaceutical University, Tokyo, Japan; 2Corporate Affairs, Health & Value, Pfizer Japan ...
Akazawa M, Mimura W, Togo K, Ebata N, Harada N, Murano H, Abraham L, Fujii K   +7 more
doaj  

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study. [PDF]

, 2019
BACKGROUND AND OBJECTIVES: There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release,
Gimbel, Joseph S., Hu, Jia, Lee, Gwo-Chin, Pollack, Richard A., Viscusi, Eugene R.   +4 more
core   +1 more source

Optimizing Peripheral Nerve Block Placement in Hip Surgery: A Cadaveric Study Mapping the Posterior Cutaneous Innervation

Clinical Anatomy, EarlyView.
ABSTRACT Optimizing analgesia after hip surgery enables more rapid recovery. However, peripheral nerve blocks (PNBs) often fail to provide adequate pain relief in the posterolateral hip as they typically target the lateral cutaneous nerve of the thigh (LCNT).
Ziki Gurney, Kenneth Saw Kai Wei, Leia Boote, Daniel Gareth Stolady, Benjamin Fox, Alan R. Norrish   +5 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Policies, adaptations, and ongoing challenges to naloxone, buprenorphine and nonprescription syringe access across four-states: Findings from an environmental scan and key informant interviews

Drug and Alcohol Dependence Reports
Background: As the US opioid-involved morbidity and mortality increase, uptake and implementation of evidence-based interventions remain key policy responses.
Anthony S. Floyd, Joseph Silcox, Gail Strickler, Thuong Nong, Malcolm Blough, Derek Bolivar, Megan Rabin, Jeffrey Bratberg, Adriane N. Irwin, Daniel M. Hartung, Ryan N. Hansen, Robert Bohler, Traci C. Green   +12 more
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