Results 161 to 170 of about 659,970 (390)

Differential behaviour of LPH‐(61–91)‐peptide in different model systems: Comparison of the opioid activities of LPH‐(61–91)‐peptide and its fragments [PDF]

, 1977
András Z. Rónai, László Gráf, József I. Székely, Zsuzsa Dunai-Kovàcs, S. Bajusz   +4 more
openalex   +1 more source

Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects

Nature Communications, 2019
Opioid analgesics are powerful pain relievers; however, over time, pain control diminishes as analgesic tolerance develops. The molecular mechanisms initiating tolerance have remained unresolved to date.
A. Kliewer, F. Schmiedel, S. Sianati, A. Bailey, J. Bateman, E. Levitt, John T. Williams, M. Christie, S. Schulz   +8 more
semanticscholar   +1 more source

Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

British Journal of Clinical Pharmacology, EarlyView.
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová, Svetlana Skurtveit, Marte Handal, Geana Paula Kurita, Torgeir Gilje Lid, Ingvild Odsbu, Mikael Hoffmann   +6 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio as an Indicator of Opioid-Induced Immunosuppression After Thoracoscopic Surgery: A Randomized Controlled Trial

Journal of Pain Research, 2022
Qi Chen,1,* Jingqiu Liang,2,* Ling Liang,2 Zhongli Liao,2 Bin Yang,3 Jun Qi2 1Department of Anesthesiology, Chongqing University Cancer Hospital, Chongqing, People’s Republic of China; 2Chongqing Cancer Multi-Omics Big Data Application ...
Chen Q, Liang J, Liang L, Liao Z, Yang B, Qi J   +5 more
doaj  

Opioid Effects on Computer-Derived Sleep and EEG Parameters in Nondependent Human Addicts [PDF]

, 1979
David C. Kay, Wallace B. Pickworth, Gary L. Neidert, David Falcone, P. Fishman, Ekkehard Othmer   +5 more
openalex   +1 more source

Combination vs. single‐drug nonprescription analgesics for acute pain management: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Combining nonprescription analgesics with different mechanisms of action has been proposed as a rational strategy to optimize the management of acute pain. This review assessed the efficacy and safety of nonprescription analgesics, including paracetamol (acetaminophen), metamizole and nonsteroidal anti‐inflammatory drugs (NSAIDs) used in combination vs.
Ali Mobasheri, Bart Morlion, Vidhu Sood Sethi, Mary Cardosa, Oscar Della Pasqua, Pranab Kalita   +5 more
wiley   +1 more source

Policies, adaptations, and ongoing challenges to naloxone, buprenorphine and nonprescription syringe access across four-states: Findings from an environmental scan and key informant interviews

Drug and Alcohol Dependence Reports
Background: As the US opioid-involved morbidity and mortality increase, uptake and implementation of evidence-based interventions remain key policy responses.
Anthony S. Floyd, Joseph Silcox, Gail Strickler, Thuong Nong, Malcolm Blough, Derek Bolivar, Megan Rabin, Jeffrey Bratberg, Adriane N. Irwin, Daniel M. Hartung, Ryan N. Hansen, Robert Bohler, Traci C. Green   +12 more
doaj  

Are There Any Differences Between Expressive Suppression and Cognitive Reappraisal in Opioids and Stimulant Dependent Patients? [PDF]

, 1970
Banafsheh Mohajerin, Behrouz Dolatshahi, Abbas Pour Shahbaz, Ali Farhoudian   +3 more
openalex   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Opioid Use Patterns After Nonsurgical Management of Distal Radius Fractures: A Call for Opioid Stewardship

Journal of Hand Surgery Global Online
Purpose: While most opioid research focuses on postoperative use, limited data exist on prescribing patterns in nonsurgical management of common injuries such as distal radius fractures (DRFs).
Sina Ramtin, MD, Sara Khan, BS, Vijay Chhabra, BA, Wali Pirzada, BS, Mohammad Khak, MD, Asif M. Ilyas, MD, MBA   +5 more
doaj