Results 161 to 170 of about 38,144 (289)

GABAB receptor‐mediated modulation of sensory neuron excitability: Roles of CaV2.2, G‐protein‐coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation‐activated cyclic nucleotide‐gated (HCN) channels in human and mouse nociception

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage‐gated calcium and potassium channels by G protein‐coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the analgesic peptide α‐conotoxin Vc1.1 activate GABAB receptors (GABABR), resulting in inhibition of CaV2.2 and ...
Mariana Brizuela   +4 more
wiley   +1 more source

Potent, Orally Bioavailable Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery ofN,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4′-piperidine]-4-yl)benzamide (ADL5859)

open access: green, 2008
Bertrand Le Bourdonnec   +22 more
openalex   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Effectiveness of adjunctive, personalised psychosocial intervention for non-response to opioid agonist treatment: Study protocol for a pragmatic randomised controlled trial

open access: gold, 2016
John Marsden   +9 more
openalex   +2 more sources

Harnessing telemedicine to deliver patient-centered opioid agonist treatment within a community-based harm reduction service: a mixed methods evaluation. [PDF]

open access: yesHarm Reduct J
Høj SB   +10 more
europepmc   +1 more source

Active Gallbladder Lavage Using a Double‐pigtail Plastic Stent Delivery System During Endoscopic Ultrasound‐guided Gallbladder Drainage (With Video)

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Endoscopic ultrasound‐guided gallbladder drainage using a double‐pigtail plastic stent (DPPS) harbors the risk of bile leakage and pneumoperitoneum through the anastomosis site. When the inner sheath of the DPPS system is retracted halfway back into the stent, multiple side holes emerge on the stent end, which accelerates the active gallbladder lavage.
Tesshin Ban   +7 more
wiley   +1 more source

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