Results 91 to 100 of about 410,228 (317)

Synthesis, biological evaluation, and SAR studies of 14β-phenylacetyl substituted 17-cyclopropylmethyl-7, 8-dihydronoroxymorphinones derivatives : Ligands with mixed NOP and opioid receptor profile [PDF]

open access: yes, 2018
© 2018 Kumar, Polgar, Cami-Kobeci, Thomas, Khroyan, Toll and Husbands.A series of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydronoroxymorphinone compounds has been synthesized and evaluated for affinity and efficacy for mu (MOP), kappa (KOP), and ...
Cami-Kobeci   +47 more
core   +2 more sources

A new extended release formulation (OROS®) of hydromorphone in the management of pain

open access: yesTherapeutics and Clinical Risk Management, 2008
Sharon M WeinsteinUniversity of Utah, Huntsman Cancer Institute, Salt Lake City, Utah, USAAbstract: Opioid analgesics are essential in the treatment of moderate to severe cancer-related pain.
Sharon M Weinstein
doaj  

Use of metamizole and other non-opioid analgesics in Switzerland between 2014 and 2019: an observational study using a large health insurance claims database

open access: yesSwiss Medical Weekly
OBJECTIVE: To investigate claims patterns for metamizole and other non-opioid analgesics in Switzerland. To characterise users of these non-opioid analgesics regarding sex, age, comedications and canton of residence.
Stephan Gut   +7 more
doaj   +1 more source

Infiltrative analgesia of the skin flap in children with craniosynostosis after reconstructive surgery on skull bones

open access: yesВестник анестезиологии и реаниматологии, 2020
The objective of the study is to evaluate the effectiveness of analgesia by infiltration of the skin flap with local anesthetic in children with craniosynostosis after reconstructive surgery.Materials and subjects.
O. N. Pulkina   +3 more
doaj   +1 more source

Abuse-deterrent formulations of prescription opioid analgesics in the management of chronic noncancer pain.

open access: yesPain Management, 2016
Misuse, abuse and diversion of prescription opioid analgesics represent a global public health concern. The development of abuse-deterrent formulations (ADFs) of prescription opioid analgesics is an important step toward reducing abuse and diversion of ...
M. Hale   +4 more
semanticscholar   +1 more source

Non-opioid analgesic poisoning [PDF]

open access: yesClinical Medicine, 2003
L'abus medicamenteux des antiinflammatoires, du paracetamol et de l'aspirine est tres important dans de nombreux pays ...
Glyn Volans   +3 more
openaire   +3 more sources

Comparison of opioid prescribing by dentists in the United States and England [PDF]

open access: yes, 2019
Importance: The United States consumes most of the opioids worldwide despite representing a small portion of the world\u27s population. Dentists are one of the most frequent US prescribers of opioids despite data suggesting that nonopioid analgesics are ...
Calip, Gregory S   +7 more
core   +1 more source

Clinically important drug interactions with opioid and non-opioid analgesics [PDF]

open access: yesArhiv za farmaciju, 2019
Patients often seek advise from doctors and pharmacists about pain treatment. Opioid and non-opioid analgesics are the most commonly used drugs in the treatment of pain, but they have potential for pharmacodynamic and pharmacokinetic drug-drug ...
Vezmar-Kovačević Sandra   +4 more
doaj  

Non-opioid analgesics in contemporary treatment of pain [PDF]

open access: yesArhiv za farmaciju, 2018
Pain is a symptom of most diseases that can significantly impair the patient's quality of life. In many diseases it is impossible to eliminate the cause of pain therefore the real goal of treatment is the removal of pain as a symptom, by application of ...
Tomić Maja, Pecikoza Uroš, Micov Ana
doaj   +1 more source

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study. [PDF]

open access: yes, 2019
BACKGROUND AND OBJECTIVES: There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release,
Gimbel, Joseph S.   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy