Results 121 to 130 of about 410,228 (317)

The Influence of Gene Polymorphism OPRM1 118A/G on the Perception of Pain and Pharmacodynamics of Narcotic Analgesics

open access: yesОбщая реаниматология, 2014
The polymorphism of μ-opioid receptor is one of the most studied polymorphisms that affect the activity of narcotic analgesics. Despite that there are a large number of publications dealing with the problem, the obtained results are not being currently ...
V. M. Zhenilo, O. A. Makharin
doaj   +1 more source

National consumption of opioid and nonopioid analgesics in Croatia: 2007–2013

open access: yesTherapeutics and Clinical Risk Management, 2015
Darko Krnic,1 Andrea Anic-Matic,2 Svjetlana Dosenovic,2 Pero Draganic,1 Sasa Zezelic,1 Livia Puljak2 1Agency for Medicinal Products and Medical Devices, Zagreb, 2Laboratory for Pain Research, School of Medicine, University of Split, Split, Croatia ...
Krnic D   +5 more
doaj  

Exposure to prescription opioid analgesics in utero and risk of neonatal abstinence syndrome: population based cohort study

open access: yesBritish medical journal, 2015
Objective To provide absolute and relative risk estimates of neonatal abstinence syndrome (NAS) based on duration and timing of prescription opioid use during pregnancy in the presence or absence of additional NAS risk factors of history of opioid misuse
R. Desai   +7 more
semanticscholar   +1 more source

Managing Prolonged Pain After Surgery: Examining the Role of Opioids. [PDF]

open access: yes, 2018
A notable minority of patients experience persistent postsurgical pain and some of these patients consequently have prolonged exposure to opioids. Risk factors for prolonged opioid use after surgery include preoperative opioid use, anxiety, substance ...
Pozek, John-Paul J.   +2 more
core   +1 more source

The atomistic level structure for the activated human κ-opioid receptor bound to the full Gi protein and the MP1104 agonist [PDF]

open access: yes, 2020
The kappa opioid receptor (κOR) is an important target for pain therapeutics to reduce depression and other harmful side effects of existing medications.
Goddard, William A., III   +2 more
core   +1 more source

A pharmacogenetics approach to pain management

open access: yesNeuropsychopharmacology Reports, 2018
Introduction Opioid analgesics are widely used as effective analgesics for the treatment of moderate‐to‐severe pain. However, the analgesic efficacy of opioids is well known to vary widely among individuals, and effective pain treatment is hampered by ...
Kaori Yoshida   +5 more
doaj   +1 more source

Opioid Atlas: Mapping Access to Pain Medication [PDF]

open access: yesarXiv, 2016
Opiates are some of the most effective pain relief medications available for patients suffering from cancer and surgery-related pain. Despite the affordability and effectiveness of these medications, access to opiates is highly geographically variable. Pain researchers have attributed geographic variation to various factors including the fear of opioid
arxiv  

Discovering Opioid Use Patterns from Social Media for Relapse Prevention [PDF]

open access: yesarXiv, 2019
The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral interventions for impacted individuals.
arxiv  

EFFECTS OF A NIGHT-TIME OPIOID INFUSION ON THE POSTOPERATIVE ANALGESIC REQUIREMENT [PDF]

open access: bronze, 1991
Robert K. Parker   +2 more
openalex   +1 more source

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