Results 151 to 160 of about 1,267,582 (207)

Artificial intelligence across the continuum of care for the aging musculoskeletal patient: From longitudinal phenotyping to personalized surgery and recovery monitoring

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Musculoskeletal care is being reshaped by population aging, multimorbidity, frailty, osteoporosis, sarcopenia, polypharmacy and increasing vulnerability to postoperative loss of independence. Artificial intelligence (AI) has entered orthopaedic research, but its clinical translation remains constrained. Many models address isolated diagnostic,
Felix C. Oettl   +8 more
wiley   +1 more source

Radiofrequency Ablation as a Safe and Effective Treatment for Thyroid Nodules After Lobectomy

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Background A new symptomatic nodule may develop or a preexisting nodule may grow to warrant treatment in the remaining lobe of patients who previously had a unilateral thyroid lobectomy. Conventional management often results in completion thyroidectomy, but radiofrequency ablation (RFA) offers a minimally invasive alternative to surgical ...
Yaser Bashumeel   +11 more
wiley   +1 more source

Cannabis Use and Prolonged Opioid Utilization After Head and Neck Free Flap Reconstructive Surgery

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Goal This study investigates the risk of prolonged postoperative opioid use and functional outcomes of free flap reconstruction in head and neck cancer patients with a history of cannabis use. Methods Patients undergoing head and neck free flap reconstruction (2005–2025) were identified using the TriNetX database and stratified by cannabis use.
Ella P. Jackert   +5 more
wiley   +1 more source

Mass Spectrometry in Authentication and Forensic Approaches for Determining the Origin of Hazardous Chemicals

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Identification of a chemical agent yields insights into its physicochemical properties. By examining the intrinsic characteristics and environment of a compound, information about its history can be gathered. The main objective of authentication/forensic approaches to chemicals is to trace the history of the compound's origin, regardless of ...
Carla Orlandi   +6 more
wiley   +1 more source

The Application of Telemedicine in Surgery

open access: yesMed Research, EarlyView.
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang   +8 more
wiley   +1 more source

Cross‐Cohort Evidence Links KCNJ6 rs702859 to Impulsive–Compulsive Phenotypes in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Impulse control disorders (ICDs) and related compulsive behaviors (CBs) are frequent non‐motor complications of Parkinson's disease (PD) with a probable genetic contribution. Objective To investigate whether genetic variants involved in reward and punishment processing are associated with impulsive–compulsive phenotypes in PD ...
Sergio García‐Díaz   +21 more
wiley   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu   +15 more
wiley   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith   +5 more
wiley   +1 more source

Malnutrition in cancer surgery: A retrospective study on screening practices and outcomes

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Preoperative nutrition risk screening and referral for optimization are recommended for patients undergoing cancer surgery; however, despite high‐risk individuals being identified, referral remains variable. This study aimed to determine the prevalence of preoperative undernutrition risk and body mass index (BMI)‐defined ...
Noha Elsherbini   +9 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

open access: yesNeuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi   +5 more
wiley   +1 more source

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