Results 151 to 160 of about 59,093 (301)

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Fashioning Appropriate Regulation of Opioids for Palliative Care [PDF]

, 2018
Palliative care specialists, who care for patients with serious, life-limiting illnesses such as cancer, are experts in evaluating and managing acute pain.
Albrecht, Tara, Cassel, J. Brian, Del Fabbro, Egidio, Noreika, Danielle, Tsukanov, Jessica   +4 more
core   +1 more source

Trends in novel opioid use and detections in exposures and police drug seizures in New South Wales

Drug and Alcohol Review, EarlyView.
Abstract Introduction Novel opioids, including non‐medical and non‐opium‐based opioids such as fentanyl analogues and nitazenes, pose a significant risk of harm due to their high potency. There is little published data on novel opioid detections and harms in Australia, yet they are implicated in multiple deaths.
Janette L. Smith, Jared Brown, David Atefi, Thanjira Jiranantakan, Vanessa Shaw, Christopher Ewers, Lorraine du Toit‐Prinsloo, Darren M. Roberts   +7 more
wiley   +1 more source

Engagement in a National Naloxone Programme among people who inject drugs [PDF]

, 2016
Bird, Sheila M., Goldberg, David, Hutchinson, Sharon J., McAuley, Andrew, Munro, Alison, Taylor, Avril   +5 more
core   +2 more sources

A Scoping Review of the Emergence of Novel Synthetic Opioids in Australian Drug Markets: What Does This Mean for Harm Reduction Responses?

Drug and Alcohol Review, EarlyView.
ABSTRACT Issues Rising synthetic opioid deaths in North America, and the emergence of nitazene harms has driven concern about novel synthetic opioids (NSO) in Australia. This scoping review aimed to map what is known about NSOs in Australia. Approach Scoping review of peer‐reviewed and grey literature on NSO detections and harms.
Emmanuel Mammoliti, Suzanne Nielsen, Amanda Roxburgh   +2 more
wiley   +1 more source

Dealing With Opioid Overdose [PDF]

The Journal for Nurse Practitioners, 2016
openaire   +2 more sources

Searching for a Needle in a Haystack: Chemical Analysis Reveals Nitazenes Found in Drug Paraphernalia Residues

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction A group of synthetic opioids, the nitazenes, is appearing in the illicit drug market. Monitoring these novel psychoactive substances is challenging due to constantly evolving analogues and the small amounts of these potent drugs that are consumed.
Emma L. Keller, Brock Peake, Bradley S. Simpson, Marie Longo, Stephen Trobbiani, Jason M. White, Cobus Gerber   +6 more
wiley   +1 more source

Role of Dentists in Prescribing Opioid Analgesics and Antibiotics: An Overview [PDF]

, 2018
Ackerman, Al-Huwayrini, Aldous, Aminoshariae, Amir Azarpazhooh, Ashrafioun, Baker, Baur, Bax, Birrenbach, Bohnert, Budnitz, Cabana, Cadieux, Center for Disease Control and Prevention, Christopher Okunseri, Conly, Cooper, Crane, Cunha, Dar-Odeh, De-Bem, Denisco, Dionne, Dirks, Dodd, Dowell, Drekonja, Ellison, European Centre for Disease Prevention and Control (CDC), Fazakerley, Fleming-Dutra, Forbes, Gonzales, Gordon, Grimshaw, Grol, Guy, Haas, Hasegawa, Hicks, Irvine, John, Kakoei, Katie J. Suda, Katz, Kumar, Lam, Levy, Lewis, Little, Logan, Longman, Ma, Martin, McCauley, Mutlu, Nima Laghapour, Ong, Ostini, Pallasch, Pallasch, Pallasch, Palmer, Palmer, Paluck, Paulozzi, Porucznik, Pynn, Ralph Dana, Rasubala, Rigoni, Rodriguez-Nunez, Runciman, Saadat, Samaranayake, Sawair, Schumock, Seager, Segura-Egea, Shehab, Smith, Spurling, Steed, Steinmetz, Substance Abuse and Mental Health Services Administration, Suda, Sweeney, Thornhill, Thornhill, Tufts Health Care Institute, Van der Sanden, Vanderweil, Vessal, Volkow, Wall, Wang, Wright, Yingling, Zimmerman   +99 more
core   +2 more sources

Geographic Differences in Public Opinion on Drug Policy: Understanding Patterns of Support and ‘Don't Know’ Responses

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction Policymakers and advocates often rely on public opinion to support or oppose certain policies, with national surveys providing an important data source. Different geographic areas have socio‐political specificity and are impacted by drug policies in different ways; yet there has been little analysis of public opinion accounting ...
Paul Kelaita, Keelin O'Reilly, Alison Ritter   +2 more
wiley   +1 more source

Emergence of Medetomidine in the Unregulated Drug Supply and Its Association With Hallucinogenic Effects

Drug and Alcohol Review, EarlyView.
ABSTRACT Introduction The unregulated drug supply in the United States is rapidly evolving, and veterinary tranquillisers have emerged as adulterants of concern, especially in illicitly‐manufactured fentanyl. Following the proliferation of xylazine, medetomidine, a more potent sedative, has recently appeared in multiple US states.
Adams L. Sibley, Madigan L. Bedard, Samuel Tobias, Brooke A. Chidgey, Irina G. Phillips, Alice Bell, Nabarun Dasgupta   +6 more
wiley   +1 more source